Protein Alignment Indy and Slc13a5

DIOPT Version :10

• Sequence 1: NP_730363.2
• Gene: Indy / 40049
• FlyBaseID: FBgn0036816
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_017170015.1
• Gene: Slc13a5 / 237831
• MGIID: 3037150
• Length: 610
• Species: Mus musculus
• Alignment Length: 543
• Identity: 182/543 - (33%)
• Similarity: 311/543 - (57%)
• Gaps: 30/543 - (5%)

  Fly    24 GEQPQPP---VKCSNFFANHWKGLVVFL-VPLLCLPVMLLNEGAEFRCMYLLLVMAIFWVTEALP 84
            ||..|.|   :..:......:|...:.| .|:|.||:::|......||.|::::||::|.|:.:|
Mouse    28 GESSQSPFHAMDSAKTCVTKFKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIP 92

  Fly    85 LYVTSMIPIVAFPIMGIMSSDQTCRLYFKDTLVMFMGGIMVALAVEYCNLHKRLALRVIQIVGCS 149
            :.|||::|::.||::.::.|.|.|..|.|||.::|:|.::||:|||...||||:|||::..||..
Mouse    93 VAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTK 157

  Fly   150 PRRLHFGLIMVTMFLSMWISNAACTAMMCPIIQAVLEELQAQGVC--------------KINHEP 200
            |.||..|.:.||.||||||||.|.||||.||::|:|:::.|....              |.:..|
Mouse   158 PSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANTAVEASLGTLELLDKNKTSELP 222

  Fly   201 QYQIVGGNKKNNEDEPPYPTKITLCYYLGIAYASSLGGCGTIIGTATNLTFKGIYEARFKNSTEQ 265
            ..|:|..:....|.|......:....:|.:.|::|:||..|:.||..|:...|..:..|.:|.:.
Mouse   223 GSQVVFEDPNVQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSKDV 287

  Fly   266 MDFPTFMFYSVPSMLVYTLLTFVFLQWHFMGLWRPKSKEAQEV--QRGREGADVAKKVIDQRYKD 328
            :::.::..::.|:|::..:|.:::||..:|   |...|:....  ::.|:...:|.||:::.|:.
Mouse   288 LNYASWFGFAFPNMVMMLVLAWLWLQCLYM---RHNLKKTCICCGEKKRDTEKIAYKVLNEEYQK 349

  Fly   329 LGPMSIHEIQVMILFIFMVVMYFTRKPGIFLGWADLL----NSKDIRNSMPTIFVVVMCFMLPAN 389
            ||.:|..|..|:..|..:|:::|:|.||...||....    |:..|.::...|||.::.|::|:.
Mouse   350 LGSLSYPECNVLFCFTLLVILWFSRDPGFMPGWLSFAWVEGNTVHITDATVAIFVAILLFIIPSQ 414

  Fly   390 YAFLRYC--TRRGGPVPTGPTPSLITWKFIQTKVPWGLVFLLGGGFALAEGSKQSGMAKLIGNAL 452
            .....:.  |......|..| |:|:.||..|.||||.:|.|||||||:|:|.:.||::|.:...:
Mouse   415 KPKFNFSSQTEEERKTPFYP-PALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQM 478

  Fly   453 IGLKVLPNSVLLLVVILVAVFLTAFSSNVAIANIIIPVLAEMSLAIEIHPLYLILPAGLACSMAF 517
            ..|:::..:|:.|::..:....|..:||||...:.:|:.|.|:.:|.|||||:::|..::.|:||
Mouse   479 EPLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLAF 543

  Fly   518 HLPVSTPPNALVAGYANIRTKDM 540
            .|||:|||||:|..|.::|..||
Mouse   544 MLPVATPPNAIVFAYGHLRVVDM 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy	NP_730363.2	CitT	120..545	CDD:440239	149/443 (34%)
Slc13a5	XP_017170015.1	CitMHS	<48..200	CDD:460985	68/151 (45%)
		CitT	128..566	CDD:440239	147/441 (33%)