Protein Alignment Indy and nac-3

DIOPT Version :9

• Sequence 1: NP_730363.2
• Gene: Indy / 40049
• FlyBaseID: FBgn0036816
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001022673.1
• Gene: nac-3 / 176429
• WormBaseID: WBGene00003519
• Length: 566
• Species: Caenorhabditis elegans
• Alignment Length: 551
• Identity: 186/551 - (33%)
• Similarity: 293/551 - (53%)
• Gaps: 59/551 - (10%)

  Fly    43 GLVVFLVPLLCLPVMLLNEGAEFRCMYLLLVMAIFWVTEALPLYVTSMIPIVAFPIMGIMSSDQT 107
            |||:.|.||. ...||..||.|::|.|.:.::|::|::|.:||.||:|:|:|.||::|::.::.|
 Worm    54 GLVLVLTPLF-FGQMLNWEGPEWKCAYCVCIIAVYWMSEVMPLAVTAMLPVVLFPLVGVLDANTT 117

  Fly   108 CRLYFKDTLVMFMGGIMVALAVEYCNLHKRLALRVIQIVGCSPRRLHFGLIMVTMFLSMWISNAA 172
            .:.|..||..:|:||:::|.|||.|:||:|:||.|::.||..|:.:..|.:.||..||.:|||.|
 Worm   118 AKEYMNDTNFLFIGGLIMAAAVEKCDLHERVALSVLRCVGSEPKWIMLGFMTVTALLSSFISNTA 182

  Fly   173 CTAMMCPIIQAVLEELQAQGVCKINHEPQYQIVGGNKKNNEDEPPYPTKITLCYYLGIAYASSLG 237
            .||||.||.|:|:::|    :....|.|         .|.|.......|:.....|.|.:|:::|
 Worm   183 TTAMMVPIGQSVVQQL----ISSFQHHP---------TNGERGRLGCKKMATGLVLSICFAANIG 234

  Fly   238 GCGTIIGTATNLTFKGIYEARFKNSTEQMDFPTFMFYSVPSMLVYTLLTFVFLQWHFMGLWRPKS 302
            |.||..||.:||...|...|.|......:::.|::|::.|.||:...:.::.|...|:
 Worm   235 GTGTATGTPSNLVMLGQLSALFPKVDGSLNYVTWIFFAYPLMLLCLFVAWMTLVSFFL------- 292

  Fly   303 KEAQEVQRGREGADVAKKVIDQRYKDLGPMSIHEIQVMILFIFMVVMYFTRKPGIFLGWADLLNS 367
            ::|.|..      :...:::..||.:|..|:..|..|.:.|..::.::..|.||:..|:......
 Worm   293 RDAPEKD------EAVTEMLKTRYNELPRMTYAEKSVFVCFCILLSLWVFRNPGVVPGFGVFFKK 351

  Fly   368 KDIRNSMPTIFVVVMCFMLP------ANYAFLRYCTRRGGPVPTGPTPSLITWKFIQTKVPWGLV 426
            ....::...:.|..:.|:||      |.|.......:||         .|:.||.:|...||.:|
 Worm   352 GAYTDATSAMIVAFLLFVLPSERPDLATYIKKEDLKKRG---------CLMDWKTMQETFPWSVV 407

  Fly   427 FLLGGGFALAEGSKQSGMAKLIGNALIGLKVLPNSVLLLVVILVAVFLTAFSSNVAIANIIIPVL 491
            .|||||||||.|.|:||::.||||:|..::.||..:|.|:.:|:|:.:|...||...|:|.:|::
 Worm   408 LLLGGGFALAAGVKESGLSLLIGNSLSSIEHLPLWILQLLTMLIAMVITNICSNTVTASIFVPIV 472

  Fly   492 AEMSLAIEIHPLYLILPAGLACSMAFHLPVSTPPNALVAGYANIRTKDMAIAGIGPTIITIITLF 556
            |.::.....||..|:||..||.|.||..||.|||||:|.|...::..|||..|      .||:|.
 Worm   473 ATLAQRAGHHPFTLMLPTTLASSFAFIFPVGTPPNAIVFGSGMVKVSDMAFVG------GIISLE 531

  Fly   557 VFCQTWGLVVYPN--------LNSFPEWAQI 579
            :...|   |:|.|        |..||.||.|
 Worm   532 LLVLT---VLYMNSIAYLTLPLLEFPTWAII 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy	NP_730363.2	SLC13_permease	68..545	CDD:238535	160/482 (33%)
		dass	70..545	CDD:273267	159/480 (33%)
nac-3	NP_001022673.1	SLC13_permease	83..543	CDD:238535	167/503 (33%)
		dass	84..539	CDD:273267	165/498 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	316	1.000	Domainoid score	I685
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2965
Inparanoid	1	1.050	329	1.000	Inparanoid score	I1442
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57284
OrthoDB	1	1.010	-	-		D282824at33208
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	1	1.000	-	-		mtm4842
orthoMCL	1	0.900	-	-		OOG6_101290
Panther	1	1.100	-	-	O	PTHR10283
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2228
SonicParanoid	1	1.000	-	-		X273
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.010