DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cat and CAT1

DIOPT Version :9

Sequence 1:	NP_536731.1	Gene:	Cat / 40048	FlyBaseID:	FBgn0000261	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_564121.1	Gene:	CAT1 / 838652	AraportID:	AT1G20630	Length:	492	Species:	Arabidopsis thaliana

Alignment Length:	487	Identity:	210/487 - (43%)
Similarity:	289/487 - (59%)	Gaps:	28/487 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRERIPERVVHAKGAGAFGYFEVTHDIT 90
            ||.:|||:...::|.|||.||||||:|.:.|:::::|||||||||||||:||.|.|:||||||||
plant    18 TTNSGAPVWNNNSSLTVGTRGPILLEDYHLLEKLANFDRERIPERVVHARGASAKGFFEVTHDIT 82

  Fly    91 QYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAVKFYTEDGVWDLVGNNTPVFFIRD 155
            |..:|........:||:.||||||..|.||.:|.||||||||||||.:|.:||||||.||||:||
plant    83 QLTSADFLRGPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFVRD 147

  Fly   156 PILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQVCILFSDRGTPDGYCHMNGYGSHTFKL 220
            .:.||..:|..|.||::|:::.....||.:..|||.|....||.|.|.|..|.||.|.|.:|:.|
plant   148 GMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFSFLFDDLGIPQDYRHMEGAGVNTYML 212

  Fly   221 INAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRDLYNRIKTCKFPSWTMYIQVMTYE 285
            ||..|:..|.|||:|...|||.|..:.|.::...:..::.:|||:.|....:|.|.:::|||...
plant   213 INKAGKAHYVKFHWKPTCGIKCLSDEEAIRVGGANHSHATKDLYDSIAAGNYPQWNLFVQVMDPA 277

  Fly   286 QAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEVEQIAFSPAHLVPGVEPSPDKMLH 350
            ...||.::|.||||:|.:...||.|||::||::|..|:|.|.|||||.||.:|||:..|.||:|.
plant   278 HEDKFDFDPLDVTKIWPEDILPLQPVGRLVLNKNIDNFFNENEQIAFCPALVVPGIHYSDDKLLQ 342

  Fly   351 GRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIENFQRDGAMNVTDNQDGAPNYFPNSFNGPQECPR 415
            .|:|||:|:.||||||||||:|||.| |....|...||.||.. ::|...||||:..:..:...:
plant   343 TRIFSYADSQRHRLGPNYLQLPVNAP-KCAHHNNHHDGFMNFM-HRDEEVNYFPSRLDPVRHAEK 405

  Fly   416 ARALSSCCPVTGDVYRYSSGDTEDNF-GQVTDF---------WVHVLDKCAKKRLVQNIAGHLSN 470
            .......|          ||:.|..| |:..:|         |    |...::|.|:.....||.
plant   406 YPTTPIVC----------SGNREKCFIGKENNFKQPGERYRSW----DSDRQERFVKRFVEALSE 456

  Fly   471 ASQFLQERA--VKNFTQVHADFGRMLTEELNL 500
            .....:.|:  :..::|.....|:.|...||:
plant   457 PRVTHEIRSIWISYWSQADKSLGQKLATRLNV 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cat	NP_536731.1	KatE	10..505	CDD:223824	210/487 (43%)
Cat	NP_536731.1	catalase_clade_3	66..498	CDD:163712	187/443 (42%)
CAT1	NP_564121.1	PLN02609	1..492	CDD:215328	210/487 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	381	1.000	Domainoid score	I161
eggNOG	1	0.900	-	-		E1_COG0753
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	384	1.000	Inparanoid score	I519
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D507937at2759
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		mtm1087
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X851
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820