DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cat and cat.1

DIOPT Version :9

Sequence 1:	NP_536731.1	Gene:	Cat / 40048	FlyBaseID:	FBgn0000261	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001016716.1	Gene:	cat.1 / 549470	XenbaseID:	XB-GENE-5918489	Length:	528	Species:	Xenopus tropicalis

Alignment Length:	493	Identity:	325/493 - (65%)
Similarity:	391/493 - (79%)	Gaps:	5/493 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAG-RDAASNQLIDYKNSQ-TVSPGAITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFD 63
            ||| ::.|..|:..:|.:: :..|..:|||.|.|:|.|....|.|||||:|:|||.|.|||:|||
Frog     1 MAGNKEKAPTQMNQWKEARGSQKPSVLTTGAGHPVGDKLNLLTAGPRGPLLVQDVVFTDEMAHFD 65

  Fly    64 RERIPERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPR 128
            ||||||||||||||||||||||||||||||.|.:|.||.||||:|.|||||.||:||.||.||||
Frog    66 RERIPERVVHAKGAGAFGYFEVTHDITQYCKANVFGKVGKRTPVAARFSTVAGEAGSPDTIRDPR 130

  Fly   129 GFAVKFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQ 193
            |||||.|||:|.|||.|||||:|||||.||||||:|:||||||||:|||||.|||.:|||||.||
Frog   131 GFAVKMYTEEGNWDLTGNNTPIFFIRDAILFPSFVHSQKRNPQTHMKDPDMVWDFWSLRPESLHQ 195

  Fly   194 VCILFSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDY 258
            |..||||||.|||:.||||||||||||:|.|.|.:|.||||||||||:||.::.|:|||::||||
Frog   196 VSFLFSDRGIPDGHRHMNGYGSHTFKLVNCKDEAVYCKFHFKTDQGIRNLTLEKAEQLAASDPDY 260

  Fly   259 SIRDLYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNY 323
            .|||||..|....:||||.|||:||:|||:||.:|||||||||...:|||||||||||.|||.||
Frog   261 GIRDLYEAIAAGNYPSWTFYIQIMTFEQAEKFPFNPFDVTKVWPHGDYPLIPVGKMVLSRNPTNY 325

  Fly   324 FAEVEQIAFSPAHLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIENFQRDG 388
            ||||||:||.|:::.||:||||||||.||||||.||||||||.||||:|||||||.::.|:||||
Frog   326 FAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVNCPYKARVANYQRDG 390

  Fly   389 AMNVTDNQDGAPNYFPNSFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLD 453
            .|..||||.|||||:||||:.|::.|:.|  .....|:.||.||:|.: :||..||.:|::.||:
Frog   391 PMCFTDNQGGAPNYYPNSFSAPEQQPQFR--EHRFRVSADVERYNSAN-DDNVTQVREFYLKVLN 452

  Fly   454 KCAKKRLVQNIAGHLSNASQFLQERAVKNFTQVHADFG 491
            :..::||.:||.|||.....|:|:|.||||:.||.|:|
Frog   453 EEERQRLCENIVGHLKECQLFIQKRTVKNFSDVHPDYG 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cat	NP_536731.1	KatE	10..505	CDD:223824	321/483 (66%)
Cat	NP_536731.1	catalase_clade_3	66..498	CDD:163712	292/426 (69%)
cat.1	NP_001016716.1	KatE	26..503	CDD:223824	318/468 (68%)
cat.1	NP_001016716.1	catalase_clade_3	68..497	CDD:163712	292/426 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	624	1.000	Domainoid score	I178
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	696	1.000	Inparanoid score	I665
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D172396at33208
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		mtm9352
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X851
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060