DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cat and ctt1

DIOPT Version :9

Sequence 1:	NP_536731.1	Gene:	Cat / 40048	FlyBaseID:	FBgn0000261	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_587682.1	Gene:	ctt1 / 2539418	PomBaseID:	SPCC757.07c	Length:	512	Species:	Schizosaccharomyces pombe

Alignment Length:	491	Identity:	253/491 - (51%)
Similarity:	327/491 - (66%)	Gaps:	20/491 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KNSQTVSPGAITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRERIPERVVHAKGAGA 79
            |:|.||.  ..||..|.||....|:..||..||:||||.:.:|...||||||||||||||||:||
pombe     4 KDSNTVP--VYTTNTGCPIFNPMAAARVGKGGPVLLQDSHLIDVFQHFDRERIPERVVHAKGSGA 66

  Fly    80 FGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAVKFYTEDGVWDLV 144
            ||.||.|.|||:|....:|.||.|:||:..||||||||.|:.||||||||||:||||::|::|:|
pombe    67 FGEFECTDDITKYTKHTMFSKVGKKTPMVARFSTVGGERGTPDTARDPRGFALKFYTDEGIFDMV 131

  Fly   145 GNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQVCILFSD-RGTPDGYC 208
            ||||||||:|||..||.||||||||||..:||..||||:|:...||.|||.||||| .|||..|.
pombe   132 GNNTPVFFLRDPAKFPLFIHTQKRNPQNDMKDATMFWDYLSQNAESIHQVMILFSDLGGTPYSYR 196

  Fly   209 HMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRDLYNRIKTCKFP 273
            .|:|:.|||:|.:|.|||..|.|:||.|:||.|.|..:.|..|..::||::.:||:..|:...:|
pombe   197 FMDGFSSHTYKFVNDKGEFYYCKWHFITNQGTKGLTNEEAAALDGSNPDHARQDLFEAIERGDYP 261

  Fly   274 SWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEVEQIAFSPAHLV 338
            |||:|:||||.::|:|::||.||:||||..|:.|:..||:..|::||.|:||::||..|||:|:|
pombe   262 SWTLYVQVMTPQEAEKYRYNIFDLTKVWPHKDVPMQRVGRFTLNQNPTNFFADIEQAGFSPSHMV 326

  Fly   339 PGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIENFQRDGAMNVTDNQDGAPNYF 403
            ||:|.|.|.:|..|.|||.||||||||.|:.|||||.| |..:.|:.|||.|||..||...|||
pombe   327 PGIEVSADPVLQVRTFSYPDTHRHRLGANFEQIPVNSP-KCPVFNYSRDGPMNVNGNQGNWPNY- 389

  Fly   404 PNSFNGPQECPRARALSSCCP------VTGDVYRYSSGDTEDNFGQVTDFWVHVLDK--CAKKRL 460
            |:|..     |.|:....  |      ..|.|..:....|:.:|.|...||.:||.|  ..:...
pombe   390 PSSIR-----PLAKVQYE--PDEGHEKWVGQVTYHMDEITDVDFEQPRAFWQNVLGKKPGQQDNF 447

  Fly   461 VQNIAGHLSNASQFLQERAVKNFTQVHADFGRMLTE 496
            |:|:|||||.|...::||....||:|.::.||.:.|
pombe   448 VKNVAGHLSGAISPVRERQYGVFTRVDSELGRRIRE 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cat	NP_536731.1	KatE	10..505	CDD:223824	253/491 (52%)
Cat	NP_536731.1	catalase_clade_3	66..498	CDD:163712	229/440 (52%)
ctt1	NP_587682.1	KatE	1..493	CDD:223824	253/491 (52%)
ctt1	NP_587682.1	catalase_fungal	37..486	CDD:163713	238/456 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	453	1.000	Domainoid score	I69
eggNOG	1	0.900	-	-		E1_COG0753
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	483	1.000	Inparanoid score	I264
OMA	1	1.010	-	-		QHG62736
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		otm47001
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	1	1.100	-	-	LDO	PTHR11465
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R169
SonicParanoid	1	1.000	-	-		X851
TreeFam	1	0.960	-	-
	14	13.860