DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14073 and YAR1

DIOPT Version :9

Sequence 1:	NP_001262022.1	Gene:	CG14073 / 40046	FlyBaseID:	FBgn0036814	Length:	2133	Species:	Drosophila melanogaster
Sequence 2:	NP_015085.1	Gene:	YAR1 / 855837	SGDID:	S000006160	Length:	200	Species:	Saccharomyces cerevisiae

Alignment Length:	154	Identity:	43/154 - (27%)
Similarity:	60/154 - (38%)	Gaps:	38/154 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1657 DERLEDTDS-----TIAGSSHLPPKVKTEMDVCREIQKWVLNKGVGQSTMHKAARQGLIDVVVYC 1716
            |.|..|.||     |...|..|       :..|:|.:.       ..:.:|.||..|.|:.|.|.
Yeast    19 DARAGDLDSLKDIFTTLVSPEL-------LSTCKESES-------DSTALHMAAANGHIETVRYI 69

  Fly  1717 LD---RMNMNPDQK------DNAGYTPLHEACTQGWLEIARILL-QYGANHSEAAQSGIRPLHGA 1771
            |:   |.|...|.|      :..|.|.||.|...|.|::.::|. :|.|:.....:.|    |.|
Yeast    70 LETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFG----HDA 130

  Fly  1772 I---ENDHEEVVR--LLLSYGADP 1790
            |   ||..:|.|.  .|..|..:|
Yeast   131 IFEAENSGKEEVETYFLKKYDVEP 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14073	NP_001262022.1	ANK	1697..1807	CDD:238125	33/109 (30%)
		ANK repeat	1697..1728	CDD:293786	12/39 (31%)
		Ank_2	1702..1790	CDD:289560	32/102 (31%)
		ANK repeat	1730..1761	CDD:293786	10/31 (32%)
		ANK repeat	1763..1788	CDD:293786	10/29 (34%)
		PUFD_like	2016..2129	CDD:271222
YAR1	NP_015085.1	ANK repeat	11..47	CDD:293786	9/34 (26%)
		Ank_2	20..124	CDD:403870	31/117 (26%)
		ANK repeat	49..90	CDD:293786	12/47 (26%)
		ANK repeat	92..124	CDD:293786	10/31 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960