Protein Alignment ftz-f1 and NR6A1

DIOPT Version :9

• Sequence 1: NP_524143.2
• Gene: ftz-f1 / 40045
• FlyBaseID: FBgn0001078
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: NP_201591.2
• Gene: NR6A1 / 2649
• HGNCID: 7985
• Length: 480
• Species: Homo sapiens
• Alignment Length: 565
• Identity: 134/565 - (23%)
• Similarity: 224/565 - (39%)
• Gaps: 160/565 - (28%)

  Fly   469 AGNGGAGGNSGPGNPMGGTSATPGHG-----------GEV-IDFKHLFEELCPVCGDKVSGYHYG 521
            :|.||.||::|...|.......|.:|           |.: :......:..|.:|||:.:|.|||
Human     9 SGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYG 73

  Fly   522 LLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGG 586
            :::||.|||||||::.||:||.|..:::|.:.:.||.||.|||..|||::||..:|:|.|.|.||
Human    74 IISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGG 138

  Fly   587 RNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVS 651
            |||                            |:||                 :.|.:| :|.::.
Human   139 RNK----------------------------SIGP-----------------VQISEE-EIERIM 157

  Fly   652 SLTQSPDSSPSPIAIALGQVNASTGGVIATPMNAGTGGSGGGGLNGPSSVGNGNSSNGSSNGNNN 716
            |..:..:.:                                          |..|::|.|   ::
Human   158 SGQEFEEEA------------------------------------------NHWSNHGDS---DH 177

  Fly   717 SSTGNGTSGGGGGNNAGGGGGGTNSNDGLHRNGGNG--------NSSCHEAGIGSLQNTADSKLC 773
            ||.||..|    .:|....|...:|:..:..||...        :...|...|..|
Human   178 SSPGNRAS----ESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHL--------- 229

  Fly   774 FDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQT--QLFA----------LLQKQTYNQVE 826
            |....|              ||::.:..:|:|.:.:..  ||.:          :|.:..|...:
Human   230 FSYSGH--------------SPLLPQQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQ 280

  Fly   827 VDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHL---HHRIHNGLP 888
            .:||.|:|::.|:.||.|:.|.:...||.:|.:.|...||..:|.::::|..|   ..:|...|.
Human   281 AELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELA 345

  Fly   889 DET---QLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPSVRGIV 950
            |.|   ..::.::......|:..:.:|    ..|.:|...||....:|.|||.:..||..:||:.
Human   346 DVTAKYSPSDEELHRFSDEGMEVIERL----IYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLT 406

  Fly   951 NRKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMA 995
            :...:.:.:........|:|...|....::|..|:..||||..:|
Human   407 SASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIA 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz-f1	NP_524143.2	NR_DBD_Lrh-1_like	508..600	CDD:143541	44/91 (48%)
		NR_LBD_Ftz-F1_like	794..1024	CDD:132742	54/220 (25%)
NR6A1	NP_201591.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		7/22 (32%)
		NR_DBD_GCNF_like	52..141	CDD:143543	42/88 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..150		12/63 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..199		11/85 (13%)
		Sufficient for interaction with UIMC1. /evidence=ECO:0000250	172..253		21/110 (19%)
		NR_LBD_DHR4_like	256..467	CDD:132751	50/200 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278717at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920