Protein Alignment ftz-f1 and Nr5a1

DIOPT Version :10

• Sequence 1: NP_524143.2
• Gene: ftz-f1 / 40045
• FlyBaseID: FBgn0001078
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: NP_620639.1
• Gene: Nr5a1 / 26423
• MGIID: 1346833
• Length: 462
• Species: Mus musculus
• Alignment Length: 538
• Identity: 197/538 - (36%)
• Similarity: 268/538 - (49%)
• Gaps: 103/538 - (19%)

  Fly   505 EELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCL 569
            :|||||||||||||||||||||||||||||||||.|.|||...:||.||||||||||:|||||||
Mouse    10 DELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCL 74

  Fly   570 EVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGP--DIKPTPISPGY 632
            .|||:|||||||||||||||||||||||||.|.|  ::.|:.....:...||  .:.|.|..|
Mouse    75 TVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQ--KKAQIRANGFKLETGPPMGVPPPPPPP-- 135

  Fly   633 QQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMNAGTGGSGGGGLNG 697
                |:..:...:..|:..:|...|.|.|      ||..     |..:.||          .:.|
Mouse   136 ----PDYMLPPSLHAPEPKALVSGPPSGP------LGDF-----GAPSLPM----------AVPG 175

  Fly   698 PSSVGNGNSSNGSSNGNNNSSTGNGTSGGGGGNNAGGGGGGTNSNDGLHRNGGNGNSSCHEAGIG 762
            |.....|......||
Mouse   176 PHGPLAGYLYPAFSN-------------------------------------------------- 190

  Fly   763 SLQNTADSKLCFDSGTHPSSTAD--ALIEPLRVSPMIREFVQSI-----DDREWQTQLFALLQKQ 820
               .|..|:......:.|.....  :..||....|.:.|.:..:     ::.:.:.::...||:.
Mouse   191 ---RTIKSEYPEPYASPPQQPGPPYSYPEPFSGGPNVPELILQLLQLEPEEDQVRARIVGCLQEP 252

  Fly   821 TYNQVEVDL-FELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIH 884
            ..::.:... |.|:|::.||...|.|||||..:.||:|:|.|||.|||:.||::|||||::.::.
Mouse   253 AKSRSDQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQ 317

  Fly   885 NGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFN-------ELQNKLQDLKFDMGDYVCMKFLILL 942
            .|..|...|..||...|.::.:    |.|...:       ||..:|..|:.|..::||:|||||.
Mouse   318 YGKEDSILLVTGQEVELSTVAV----QAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILF 378

  Fly   943 NPSVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMAVRGEDHLYTKHC 1007
            :..|:.:.|...|.:..:...||||||||..||...|||:.|:..|.|:.|::::.:::||.||.
Mouse   379 SLDVKFLNNHSLVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHL 443

  Fly  1008 AGSAPTQTLLMEMLHAKR 1025
            ....|...||:|||.||:
Mouse   444 GNEMPRNNLLIEMLQAKQ 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ftz-f1	NP_524143.2	NR_DBD_Lrh-1_like	508..600	CDD:143541	81/91 (89%)
		NR_LBD_Ftz-F1_like	794..1024	CDD:132742	82/242 (34%)
Nr5a1	NP_620639.1	NR_DBD_Lrh-1_like	13..105	CDD:143541	81/91 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..149		7/37 (19%)
		Atrophin-1	<147..>264	CDD:460830	24/190 (13%)
		NR_LBD_SF-1	237..460	CDD:132755	80/226 (35%)