DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg3 and ATG3

DIOPT Version :9

Sequence 1:	NP_649059.1	Gene:	Atg3 / 40044	FlyBaseID:	FBgn0036813	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_568934.1	Gene:	ATG3 / 836271	AraportID:	AT5G61500	Length:	313	Species:	Arabidopsis thaliana

Alignment Length:	345	Identity:	157/345 - (45%)
Similarity:	199/345 - (57%)	Gaps:	58/345 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 QSVLNTVKGTALNVAEYLTPVLKESKFRETGVLTPEEFVAAGDHLVHHCPTWQWAAGDETKTKPY 66
            |.:....|||    .|.:|.....|.|:|.|||:..|||.|||:||..||||.|.:||.:|.|||
plant     5 QKLHEAFKGT----VERITGPRTISAFKEKGVLSVSEFVLAGDNLVSKCPTWSWESGDASKRKPY 65

  Fly    67 LPKDKQFLITRNVPCYRR----CKQMEYVGEETLVEEESGDGGWVETH-QLNDDGTTQLEDKICE 126
            ||.||||||||||||.||    .:..|..|.|.||::|..| ||:.|| :..|.|
plant    66 LPSDKQFLITRNVPCLRRAASVAEDYEAAGGEVLVDDEDND-GWLATHGKPKDKG---------- 119

  Fly   127 LTMEETKEEMHTPDSD----------KSAPGAGGQAEDEDDDEAIDMDDFEESGMLELVDPAVAT 181
                  |||.:.|..|          :|.|...|   .|:||:..||::|:|:..:...|||...
plant   120 ------KEEDNLPSMDALDINEKNTIQSIPTYFG---GEEDDDIPDMEEFDEADNVVENDPATLQ 175

  Fly   182 TTR--KPEPEAKASPVAAASGDAEASGDSVLHTRTYDLHISYDKYYQTPRLWVVGYDEQRKPLTV 244
            :|.  ..||:                .|::|.||||||.|:|||||||||:|:.||||.|..|..
plant   176 STYLVAHEPD----------------DDNILRTRTYDLSITYDKYYQTPRVWLTGYDESRMLLQP 224

  Fly   245 EQMYEDVSQDHAKKTVTMESHPHLPGPNMASVHPCRHADIMKKIIQTVEEGGGQLGVHLYLIIFL 309
            |.:.||||||||:||||:|.||||||.: ||||||||..:|||||..:...|.:..|..||.:||
plant   225 ELVMEDVSQDHARKTVTIEDHPHLPGKH-ASVHPCRHGAVMKKIIDVLMSRGVEPEVDKYLFLFL 288

  Fly   310 KFVQTVIPTIEYDFTQNFNM 329
            ||:.:||||||||:|.:|::
plant   289 KFMASVIPTIEYDYTMDFDL 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg3	NP_649059.1	Autophagy_N	8..135	CDD:281916	60/131 (46%)
		Autophagy_act_C	219..280	CDD:281917	42/60 (70%)
		Autophagy_C	301..325	CDD:287367	15/23 (65%)
ATG3	NP_568934.1	Autophagy_N	7..138	CDD:367757	64/151 (42%)
ATG3	NP_568934.1	Autophagy_act_C	37..302	CDD:397886	142/301 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	107	1.000	Domainoid score	I2171
eggNOG	1	0.900	-	-		E1_KOG2981
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6836
Inparanoid	1	1.050	266	1.000	Inparanoid score	I941
OMA	1	1.010	-	-		QHG53787
OrthoDB	1	1.010	-	-		D1432328at2759
OrthoFinder	1	1.000	-	-		FOG0004752
OrthoInspector	1	1.000	-	-		oto2918
orthoMCL	1	0.900	-	-		OOG6_102211
Panther	1	1.100	-	-	LDO	PTHR12866
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3344
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840