DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12477 and Mkrn1

DIOPT Version :9

Sequence 1:	NP_649055.1	Gene:	CG12477 / 40040	FlyBaseID:	FBgn0036809	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_006236363.1	Gene:	Mkrn1 / 296988	RGDID:	1303251	Length:	481	Species:	Rattus norvegicus

Alignment Length:	209	Identity:	76/209 - (36%)
Similarity:	111/209 - (53%)	Gaps:	17/209 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VPSTNSPSSQIEQKGNEAIVPNYKAATAGEQGEAQAGATCTTV-----------AVRPSGVATSA 71
            ||...|.:.:..:|....:....:.......||.:.|..|..:           .:.|...|..:
  Rat   189 VPLQGSVTKEESEKEPTTVETEKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRS 253

  Fly    72 DIVKGSSSVSSHVQPSWRSSFA--RSQDKKCGICFETIMEKEG-GDKRFGILPSCNHVFCFQCIC 133
            ..:|  |.:.:| :.....|||  ||:|..||||.|.:.||.. .::|||||.:|||.:|.:||.
  Rat   254 QHIK--SCIEAH-EKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIR 315

  Fly   134 TWRHATQYAYQVTRACPECRVWSNFVCPSAFWVEEKVAKDQLINDHLAAMRARDCKYFKQGQGVC 198
            .||.|.|:..::.::|||||:.||||.||.:|||||..|.:||..:..||..:.|:||.:|:|.|
  Rat   316 KWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACRYFDEGRGSC 380

  Fly   199 LFGNKCFYKHSIPN 212
            .||..|||||:.|:
  Rat   381 PFGGNCFYKHAYPD 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12477	NP_649055.1	RING	99..153	CDD:238093	25/54 (46%)
Mkrn1	XP_006236363.1	ZnF_C3H1	55..81	CDD:214632
		ZnF_C3H1	88..110	CDD:214632
		PHA03096	<221..370	CDD:222981	57/151 (38%)
		RING	281..335	CDD:238093	25/53 (47%)
		MKRN1_C	400..479	CDD:292443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7889
eggNOG	1	0.900	-	-		E1_KOG1039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1388677at2759
OrthoFinder	1	1.000	-	-		FOG0000752
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11224
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.880