DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12477 and Mkrn3

DIOPT Version :9

Sequence 1:	NP_649055.1	Gene:	CG12477 / 40040	FlyBaseID:	FBgn0036809	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_038956927.1	Gene:	Mkrn3 / 292988	RGDID:	1311197	Length:	528	Species:	Rattus norvegicus

Alignment Length:	207	Identity:	78/207 - (37%)
Similarity:	111/207 - (53%)	Gaps:	18/207 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 QHVDTGV-LPVPSTNSPSSQIEQKGNEAIVPNYKAATAGEQGEAQAGATCTTVAVRPSGVATSAD 72
            :|:..|: :|:|.....:.....:|:....|:      ||..:     .|...|:.|...|...
  Rat   251 EHMAMGMGMPLPLCRYAARGQCLRGDRCAYPH------GEICD-----MCGQQALHPWDAAQQE- 303

  Fly    73 IVKGSSSVSSHVQPSWRSSFA--RSQDKKCGICFETIMEK-EGGDKRFGILPSCNHVFCFQCICT 134
             ....:.|.:| :.....|||  ||.||.||||.|.:.|| :..|:|||||.||||.:|.:||..
  Rat   304 -AHRRACVEAH-ERDMELSFAVQRSMDKVCGICMEVVYEKADPSDRRFGILFSCNHTYCLKCIRR 366

  Fly   135 WRHATQYAYQVTRACPECRVWSNFVCPSAFWVEEKVAKDQLINDHLAAMRARDCKYFKQGQGVCL 199
            ||.|||:..:::::||:|||.|.||.||.|||||:..|::|:..:...|..:.|:||..|.|.|.
  Rat   367 WRSATQFENRISKSCPQCRVSSGFVIPSEFWVEEEEEKEKLVQQYKEGMSQKACRYFAGGLGHCP 431

  Fly   200 FGNKCFYKHSIP 211
            ||..|||||..|
  Rat   432 FGEFCFYKHEYP 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12477	NP_649055.1	RING	99..153	CDD:238093	27/54 (50%)
Mkrn3	XP_038956927.1	zf-CCCH_4	96..117	CDD:407881
		PHA03096	<272..420	CDD:222981	60/161 (37%)
		RING-HC_MKRN1_3	328..388	CDD:319644	32/59 (54%)
		MKRN1_C	442..528	CDD:406294	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7889
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1388677at2759
OrthoFinder	1	1.000	-	-		FOG0000752
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11224
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020