DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12477 and Mkrn3

DIOPT Version :9

Sequence 1:	NP_649055.1	Gene:	CG12477 / 40040	FlyBaseID:	FBgn0036809	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_035876.2	Gene:	Mkrn3 / 22652	MGIID:	2181178	Length:	544	Species:	Mus musculus

Alignment Length:	124	Identity:	64/124 - (51%)
Similarity:	83/124 - (66%)	Gaps:	3/124 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 SFA--RSQDKKCGICFETIMEK-EGGDKRFGILPSCNHVFCFQCICTWRHATQYAYQVTRACPEC 152
            |||  ||.||.||||.|.:.|| :..|:|||||.||||.:|.:||..||.|||:..:::::||:|
Mouse   336 SFAVQRSMDKVCGICMEVVYEKADPSDRRFGILFSCNHTYCLRCIRRWRSATQFENRISKSCPQC 400

  Fly   153 RVWSNFVCPSAFWVEEKVAKDQLINDHLAAMRARDCKYFKQGQGVCLFGNKCFYKHSIP 211
            ||.|.||.||.|||||:..|::|:..:...|..:.|:||..|.|.|.||..|||||..|
Mouse   401 RVSSGFVIPSEFWVEEEEEKEKLVQQYKEGMSQKACRYFAGGLGHCPFGEFCFYKHEYP 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12477	NP_649055.1	RING	99..153	CDD:238093	27/54 (50%)
Mkrn3	NP_035876.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46
		ZnF_C3H1	92..118	CDD:214632
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	117..144
		Makorin-type Cys-His	302..329
		RING	347..401	CDD:238093	27/53 (51%)
		MKRN1_C	467..542	CDD:292443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I8071
eggNOG	1	0.900	-	-		E1_KOG1039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1388677at2759
OrthoFinder	1	1.000	-	-		FOG0000752
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11224
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880