Protein Alignment Dic4 and DIC1

DIOPT Version :9

• Sequence 1: NP_001262021.1
• Gene: Dic4 / 40039
• FlyBaseID: FBgn0036808
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_013452.1
• Gene: DIC1 / 851063
• SGDID: S000004340
• Length: 298
• Species: Saccharomyces cerevisiae
• Alignment Length: 287
• Identity: 90/287 - (31%)
• Similarity: 140/287 - (48%)
• Gaps: 33/287 - (11%)

  Fly    23 WWFGGFASMCVAFAVAPIDIVKTHMQ-IQRQKRSILGTVKRIHSLKGYLGFYDGFSAAILRQMTS 86
            ||:||.|.:.......|:|:.|..:| ....|.::...::.|.:.:|.:|.|.|.|||:|||.|.
Yeast    17 WWYGGAAGIFATMVTHPLDLAKVRLQAAPMPKPTLFRMLESILANEGVVGLYSGLSAAVLRQCTY 81

  Fly    87 TNIHFIVYDTGKK----MEYVDRDSYLGKIILGC--VAGACGSAFGIPTDLINVRMQTDMKEPPY 145
            |.:.|..||..|:    .|.:...:||    |.|  .:||.|...|...|::|:|||.|......
Yeast    82 TTVRFGAYDLLKENVIPREQLTNMAYL----LPCSMFSGAIGGLAGNFADVVNIRMQNDSALEAA 142

  Fly   146 KRRNYKHVFDGLIRIPK-EEGWKALYKGGSVAVFKSSLSTCSQIAFYDIIKT--------EVRKN 201
            ||||||:..||:.:|.: |.|.|.|:.|....:.:..|.|.||:..||:.|.        :..||
Yeast   143 KRRNYKNAIDGVYKIYRYEGGLKTLFTGWKPNMVRGILMTASQVVTYDVFKNYLVTKLDFDASKN 207

  Fly   202 ISVNDGLPLHFLTSLGTSIISSAITHPLDVVRTIMMNSRPGEFRTVFQASVHMMRFGVMGP---Y 263
            .:       |...||...::::.:..|.||::|.:||. .|:.:...:.....:|  ..||   :
Yeast   208 YT-------HLTASLLAGLVATTVCSPADVMKTRIMNG-SGDHQPALKILADAVR--KEGPSFMF 262

  Fly   264 RGFVPTIVRKAPATTLLFVLYEQLRLH 290
            ||::|:..|..|.|.|:|...|||:.|
Yeast   263 RGWLPSFTRLGPFTMLIFFAIEQLKKH 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic4	NP_001262021.1	PTZ00169	26..288	CDD:240302	86/280 (31%)
		Mito_carr	26..100	CDD:278578	25/78 (32%)
		Mito_carr	104..201	CDD:278578	35/107 (33%)
		Mito_carr	211..292	CDD:278578	25/83 (30%)
DIC1	NP_013452.1	Mito_carr	20..94	CDD:395101	24/73 (33%)
		Mito_carr	100..200	CDD:395101	36/103 (35%)
		Mito_carr	203..289	CDD:395101	26/95 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346160
Domainoid	1	1.000	84	1.000	Domainoid score	I1910
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I828
Isobase	1	0.950	-	0	Normalized mean entropy	S759
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002037
OrthoInspector	1	1.000	-	-		otm46877
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.800