DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dic4 and UCP3

DIOPT Version :9

Sequence 1:NP_001262021.1 Gene:Dic4 / 40039 FlyBaseID:FBgn0036808 Length:302 Species:Drosophila melanogaster
Sequence 2:NP_003347.1 Gene:UCP3 / 7352 HGNCID:12519 Length:312 Species:Homo sapiens


Alignment Length:293 Identity:84/293 - (28%)
Similarity:143/293 - (48%) Gaps:20/293 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 DEPEGLLPRWWFGGFASMCVAFAVAPIDIVKTHMQIQR-----------QKRSILGTVKRIHSLK 67
            |.|..:..::...|.|:........|:|..|..:|||.           |.|.:|||:..:...:
Human     8 DVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTE 72

  Fly    68 GYLGFYDGFSAAILRQMTSTNIHFIVYDTGKKM---EYVDRDSYLGKIILGCVAGACGSAFGIPT 129
            |....|:|..|.:.|||:..:|...:||:.|::   :..|..|...:|:.||..||.......||
Human    73 GPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPT 137

  Fly   130 DLINVRMQTDMKEPPYKR-RNYKHVFDGLIRIPKEEGWKALYKGGSVAVFKSSLSTCSQIAFYDI 193
            |::.||.|..:...|.:. |.|....|....|.:|||.:.|:||....:.::::..|:::..|||
Human   138 DVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDI 202

  Fly   194 IKTEVRKNISVNDGLPLHFLTSLGTSIISSAITHPLDVVRTIMMNSRPGEFRTVFQASVHMMRFG 258
            :|.::.....:.|..|.||:::.|....::.:..|:|||:|..|||.||::.:.....:.|:  .
Human   203 LKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMV--A 265

  Fly   259 VMGP---YRGFVPTIVRKAPATTLLFVLYEQLR 288
            ..||   |:||.|:.:|......::||.||||:
Human   266 QEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLK 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dic4NP_001262021.1 PTZ00169 26..288 CDD:240302 81/279 (29%)
Mito_carr 26..100 CDD:278578 24/84 (29%)
Mito_carr 104..201 CDD:278578 29/97 (30%)
Mito_carr 211..292 CDD:278578 27/81 (33%)
UCP3NP_003347.1 Mito_carr 10..110 CDD:278578 25/99 (25%)
Solcar 1 11..105 24/93 (26%)
PTZ00169 14..302 CDD:240302 82/287 (29%)
Mito_carr 112..210 CDD:278578 29/97 (30%)
Solcar 2 114..206 28/91 (31%)
Mito_carr 214..303 CDD:278578 29/87 (33%)
Solcar 3 215..300 29/86 (34%)
Purine nucleotide binding. /evidence=ECO:0000250 279..301 7/20 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0759
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D984118at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

Return to query results.
Submit another query.