Protein Alignment Dic4 and SLC25A30

DIOPT Version :10

• Sequence 1: NP_649054.1
• Gene: Dic4 / 40039
• FlyBaseID: FBgn0036808
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: XP_005266378.1
• Gene: SLC25A30 / 253512
• HGNCID: 27371
• Length: 293
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 72/265 - (27%)
• Similarity: 123/265 - (46%)
• Gaps: 41/265 - (15%)

  Fly    25 FGGFASMCVAFAVAPIDIVKTHMQIQRQK----------RSILGTVKRIHSLKGYLGFYDGFSAA 79
            :||.||:.......|||:.||.:|||.|.          |.:|..:.||...:|....|.|.:.|
Human    11 YGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSGIAPA 75

  Fly    80 ILRQMTSTNIHFIVYDTGKKMEYVDR--DSYLG-KIILGCVAGACGSAFGIPTDLINVRMQTDMK 141
            :|||.:...|....|.:.|:: :::|  |..|. .:|.|.::|...|....|||::.:|||....
Human    76 MLRQASYGTIKIGTYQSLKRL-FIERPEDETLPINVICGILSGVISSTIANPTDVLKIRMQAQSN 139

  Fly   142 EPPYKRRNYKHVFDGLI----RIPKEEGWKALYKGGSVAVFKSSLSTCSQIAFYDIIKTEVRKNI 202
            .          :..|:|    .|.::||.:.|:||.|:...::::....::..|||.|..:..:.
Human   140 T----------IQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSG 194

  Fly   203 SVNDGLPLHFLTSLGTSIISSAITHPLDVVRTIMMNSRPGEFRTVFQASVHMMRFGVMGPYRGFV 267
            .:.|.:..|||:|....:..:..::|:|||||.|||.|             ::|.|....|.|.:
Human   195 LMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQR-------------VLRDGRCSGYTGTL 246

  Fly   268 PTIVR 272
            ..:::
Human   247 DCLLQ 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dic4	NP_649054.1	Mito_carr	26..100	CDD:395101	27/83 (33%)
		Mito_carr	104..201	CDD:395101	26/103 (25%)
		Mito_carr	211..292	CDD:395101	18/62 (29%)
SLC25A30	XP_005266378.1	Mito_carr	5..100	CDD:395101	27/89 (30%)
		Mito_carr	102..191	CDD:395101	25/98 (26%)
		Mito_carr	199..>252	CDD:395101	18/66 (27%)