DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dic4 and slc25a10a

DIOPT Version :9

Sequence 1:	NP_001262021.1	Gene:	Dic4 / 40039	FlyBaseID:	FBgn0036808	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	XP_002661286.1	Gene:	slc25a10a / 100332610	ZFINID:	ZDB-GENE-131127-11	Length:	288	Species:	Danio rerio

Alignment Length:	292	Identity:	108/292 - (36%)
Similarity:	158/292 - (54%)	Gaps:	27/292 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 EGLLPRWWFGGFASMCVAFAVAPIDIVKTHMQIQRQ-KRSILGTVKRIHSLKGYLGFYDGFSAAI 80
            |..:.||:|||.||...|....|:|::|.|:|.|:: |..:.|...::....|....|:|.||::
Zfish     3 ETRVSRWYFGGIASCAAACCTHPLDLIKVHLQTQQEVKMRMTGMAVQVVRSDGVFALYNGLSASL 67

  Fly    81 LRQMTSTNIHFIVYDTGKKMEYVDRDS----------YLGKIILGCVAGACGSAFGIPTDLINVR 135
            .|||:.:...|.:|:|       .||.          :..||:|....|..|...|.|.|::|||
Zfish    68 CRQMSYSMTRFAIYET-------VRDQIASQNQGPMPFYQKILLAAFGGFTGGFIGTPADMVNVR 125

  Fly   136 MQTDMKEPPYKRRNYKHVFDGLIRIPKEEGWKALYKGGSVAVFKSSLSTCSQIAFYDIIKTEVRK 200
            ||.|||.||..||||.|..|||:|:.||||.:.|:.|.|:|..:.:|.|..|::.||..|..|..
Zfish   126 MQNDMKLPPVLRRNYAHALDGLLRVLKEEGIRKLFSGASMAASRGALVTVGQLSCYDQAKQLVLG 190

  Fly   201 NISVNDGLPLHFLTSLGTSIISSAITHPLDVVRTIMMNSRPGEFRTVFQASVHMMR-FGVMGP-- 262
            ...:.|.:..||:.|......::.:..|:|||:|.:|||: ||:|.:    :|.:. .|.:||
Zfish   191 TGLMTDNIFTHFVASFIAGGCATVLCQPMDVVKTRLMNSK-GEYRGL----IHCLSDTGKLGPKA 250

  Fly   263 -YRGFVPTIVRKAPATTLLFVLYEQLRLHFGI 293
             |:|.||..:|..|.|.|.|:..|||||:|||
Zfish   251 FYKGLVPAGIRLIPHTVLTFIFLEQLRLYFGI 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dic4	NP_001262021.1	PTZ00169	26..288	CDD:240302	98/276 (36%)
		Mito_carr	26..100	CDD:278578	24/74 (32%)
		Mito_carr	104..201	CDD:278578	44/106 (42%)
		Mito_carr	211..292	CDD:278578	32/84 (38%)
slc25a10a	XP_002661286.1	Mito_carr	12..86	CDD:278578	24/80 (30%)
		Mito_carr	94..190	CDD:278578	42/95 (44%)
		Mito_carr	195..281	CDD:278578	33/90 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D404074at33208
OrthoFinder	1	1.000	-	-		FOG0002037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810