DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6893 and ucp2

DIOPT Version :9

Sequence 1:	NP_001369058.1	Gene:	CG6893 / 40038	FlyBaseID:	FBgn0036807	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_571251.1	Gene:	ucp2 / 555812	ZFINID:	ZDB-GENE-990708-8	Length:	310	Species:	Danio rerio

Alignment Length:	297	Identity:	76/297 - (25%)
Similarity:	132/297 - (44%)	Gaps:	26/297 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RAKRVIKTKKIRPRWWSGGVAGAIAQCFTAPFDLIEARMVV-------------IKKDRGMASNL 55
            ||..|..|..:  ::...|.|..||..||.|.|..:.|:.:             ..|.||:...:
Zfish     5 RAGDVPPTATV--KFIGAGTAACIADLFTFPLDTAKVRLQIQGENKASTNMGRGPVKYRGVFGTI 67

  Fly    56 QQAIRTHGFISLYDGLSAQLLRQLTYTSMRFHLYEMGKEHL---DDPAGLLDKVLVAALAGCVAG 117
            ...:|..|..|||.||.|.|.||:::.|:|..||:..|:..   .|.||:..:::.....|.:|.
Zfish    68 STMVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSDHAGIGSRLMAGCTTGAMAV 132

  Fly   118 VVGTPMELINTRMQVNRALPKETRWNYRNVFDGLYRVTREEGFTKLYSGCFLSFMRSSLITISQN 182
            .|..|.:::..|.|...:.....|  |.:..|....:.:||||..|:.|...:..|::::..::.
Zfish   133 AVAQPTDVVKVRFQAQVSAGSSKR--YHSTMDAYRTIAKEEGFRGLWKGTGPNITRNAIVNCTEL 195

  Fly   183 AAYDQAKQIYAEFFHMKHDNTLLHLISSVTAAFVCGPIIKPIE--NLRYLRMVD---SRRLINSI 242
            ..||..|....:...|. |:...|..|:..|.|....|..|::  ..||:....   |..|..::
Zfish   196 VTYDLIKDALLKSSLMT-DDLPCHFTSAFGAGFCTTIIASPVDVVKTRYMNSAQGQYSSALNCAV 259

  Fly   243 SYMMRFGSRGPFRGMVPYVLRMVPNTVITFLSFEQLR 279
            :.:.:.|.:..::|.:|..||:....|:.|:::|||:
Zfish   260 AMLTKEGPKAFYKGFMPSFLRLGSWNVVMFVTYEQLK 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6893	NP_001369058.1	Mito_carr	20..96	CDD:395101	28/88 (32%)
CG6893	NP_001369058.1	Mito_carr	98..192	CDD:395101	22/93 (24%)
ucp2	NP_571251.1	Mito_carr	10..112	CDD:278578	29/103 (28%)
		Solcar 1	11..107		29/97 (30%)
		PTZ00169	17..300	CDD:240302	72/283 (25%)
		Mito_carr	113..209	CDD:278578	22/97 (23%)
		Solcar 2	115..204		21/90 (23%)
		Solcar 3	213..298		21/84 (25%)
		Mito_carr	218..300	CDD:278578	20/79 (25%)
		Purine nucleotide binding. /evidence=ECO:0000250	277..299		7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810