Protein Alignment CG6893 and SLC25A24

DIOPT Version :10

• Sequence 1: NP_001369058.1
• Gene: CG6893 / 40038
• FlyBaseID: FBgn0036807
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_037518.3
• Gene: SLC25A24 / 29957
• HGNCID: 20662
• Length: 477
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 65/290 - (22%)
• Similarity: 130/290 - (44%)
• Gaps: 32/290 - (11%)

  Fly    17 RWW----SGGVAGAIAQCFTAPFDLIEARMVV--IKKDR-GMASNLQQAIRTHGFISLYDGLSAQ 74
            :||    :||:|||:::..|||.|.::..|.|  .|.|: .:....:|.::..|..||:.|....
Human   193 QWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTN 257

  Fly    75 LLRQLTYTSMRFHLYEMGKEHLDDPA---GLLDKVLVAALAGCVAGVVGTPMELINTRMQVNRAL 136
            :::....|:::|..||..|:.|.:..   |..::.:..::||..|.....|||::.||:.|.:.
Human   258 VIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKT- 321

  Fly   137 PKETRWNYRNVFDGLYRVTREEGFTKLYSGC---FLSFMRSSLITISQNAAYDQAKQIYAEFFHM 198
                 ..|..::|...::.:.||....|.|.   .|..:..:.|.:   |.|:..|..:.:.|..
Human   322 -----GQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL---AVYELLKSYWLDNFAK 378

  Fly   199 KHDNT-LLHLISSVTAAFVCG-----PIIKPIENLRYLRMVDSRRLINSISYMMRF----GSRGP 253
            ...|. ::.|:.....:..||     |:......::...|::....:|.:....|.    |..|.
Human   379 DSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGL 443

  Fly   254 FRGMVPYVLRMVPNTVITFLSFEQLRVNFG 283
            :||:.|..::::|...|:::.:|.::...|
Human   444 YRGITPNFMKVLPAVGISYVVYENMKQTLG 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6893	NP_001369058.1	Mito_carr	20..96	CDD:395101	23/78 (29%)
		Mito_carr	98..192	CDD:395101	21/99 (21%)
SLC25A24	NP_037518.3	Regulatory N-terminal domain. /evidence=ECO:0000269|PubMed:24332718, ECO:0000269|PubMed:26164100	1..173
		FRQ1	18..151	CDD:444056
		Linker region. /evidence=ECO:0000269|PubMed:24332718	159..168
		C-terminal transmembrane transporter domain. /evidence=ECO:0000269|PubMed:24332718	174..477		65/290 (22%)
		PTZ00169	199..472	CDD:240302	62/281 (22%)