DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp12c1 and CYP82C2

DIOPT Version :9

Sequence 1:	NP_001287109.1	Gene:	Cyp12c1 / 40037	FlyBaseID:	FBgn0036806	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_194925.1	Gene:	CYP82C2 / 829327	AraportID:	AT4G31970	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	113/508 - (22%)
Similarity:	207/508 - (40%)	Gaps:	126/508 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 LFGM--PSTVFTFNVETFEKVYRTE--------GQWPVRG------GAEPVIHYR--NKRKDEF- 132
            ||.:  |..||.| :..|:|..:.:        |.||:.|      |.|.:: ||  .|..|::
plant     5 LFSLFVPILVFVF-IALFKKSKKPKHVKAPAPSGAWPIIGHLHLLSGKEQLL-YRTLGKMADQYG 67

  Fly   133 --------------------FKNC-------------------MG----LFG---NGAEWGKNRS 151
                                .|:|                   ||    :||   ..|.|.:.|.
plant    68 PAMSLRLGSSETFVVSSFEVAKDCFTVNDKALASRPITAAAKHMGYDCAVFGFAPYSAFWREMRK 132

  Fly   152 AVNPVLMQHRNVAIYLKPMQRVNRQFVNRIRE------IRDKESQEVPGDFMNTINHLTFE-SVA 209
            .....|:.:|.    |:.::.|....::.:.:      ::...|:.|..|..:.:..::.. .|.
plant   133 IATLELLSNRR----LQMLKHVRVSEISMVMQDLYSLWVKKGGSEPVMVDLKSWLEDMSLNMMVR 193

  Fly   210 TVALDRELGLLREANPPPEASKLFKNIEVLMDSFFDL-GV------RPSLYRYIPTPTYKKFSRA 267
            .||..|..|   ..:..||.::..:.....:.:||.| |:      .|.|..:    .::...:.
plant   194 MVAGKRYFG---GGSLSPEDAEEARQCRKGVANFFHLVGIFTVSDAFPKLGWF----DFQGHEKE 251

  Fly   268 MDEIFDTCSMYVNQAIE--RIDRKSSQGDSNDHK------SVLEQ----LLQIDRKLAV-VMAMD 319
            |.:......:.:.:.||  |..||.|....||..      |:.||    .||.|...:: ...:.
plant   252 MKQTGRELDVILERWIENHRQQRKVSGTKHNDSDFVDVMLSLAEQGKFSHLQHDAITSIKSTCLA 316

  Fly   320 MLMGGVDTTSTAISGILLNLAKNPEKQQRLREEVLSKLTSLH--SEFTVE--DMKSLPYLRAVIK 380
            :::||.:|:.:.::..:..|..|.:..::.::|:     .:|  .:..||  |:::|.|::|:||
plant   317 LILGGSETSPSTLTWAISLLLNNKDMLKKAQDEI-----DIHVGRDRNVEDSDIENLVYIQAIIK 376

  Fly   381 ESLRLYPV--TFGNARSAGADVVLDGYRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWL--RR 441
            |:|||||.  ..|: |.|..|..:.||.:.:||::|:....:.:|.|:|....||.|||::  ..
plant   377 ETLRLYPAGPLLGH-REAIEDCTVAGYNVRRGTRMLVNVWKIQRDPRVYMEPNEFRPERFITGEA 440

  Fly   442 KDDDKSDVLMNKDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHIE 494
            |:.|...       ..|..:|||.|.|.|.|..:....:.|.:|..:::|.::
plant   441 KEFDVRG-------QNFELMPFGSGRRSCPGSSLAMQVLHLGLARFLQSFDVK 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12c1	NP_001287109.1	p450	45..502	CDD:278495	113/508 (22%)
CYP82C2	NP_194925.1	CYP82	67..516	CDD:410747	95/444 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D871849at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920