DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp12c1 and CYP712A1

DIOPT Version :9

Sequence 1:	NP_001287109.1	Gene:	Cyp12c1 / 40037	FlyBaseID:	FBgn0036806	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_181754.1	Gene:	CYP712A1 / 818826	AraportID:	AT2G42250	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	114/524 - (21%)
Similarity:	207/524 - (39%)	Gaps:	100/524 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLRLTVKHGLRANSQLAATRNPDASSYVQQLESEWEGAKPFTELPGPTRWQLFRGFQKGGEYHQL 65
            ||....|..|:....||||:.|.:..           |.||.                 |..|.:
plant    21 MLYALFKWFLKEQGSLAATKLPQSPP-----------ALPFI-----------------GHLHLI 57

  Fly    66 G--MDDVMRLYKKQFGDICLIPGLFGMPSTVFTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKR 128
            |  :....:....::|.:..|  ..|....|...:.....::::           |..:::.::.
plant    58 GKVLPVSFQSLAHKYGPLMEI--RLGASKCVVVSSSSVAREIFK-----------EQELNFSSRP 109

  Fly   129 KDEFFKNCMGLFGNGAEWGKNRSAVNPVLMQHRNVAIYLKPMQRVNRQFVNRIREIRDKESQE-- 191
            :          ||: ||:.|.|.: ..||.|:.:...::|.:.......|.::.:..|...:|
plant   110 E----------FGS-AEYFKYRGS-RFVLAQYGDYWRFMKKLCMTKLLAVPQLEKFADIREEEKL 162

  Fly   192 -------------VPGDFMNTINHLTFESVATVALD-RELGLLREANPPPEASKLFKNIEVLMDS 242
                         :|.|..:.....|...:..:|:. |..|...||          :.|..|:..
plant   163 KLVDSVAKCCREGLPCDLSSQFIKYTNNVICRMAMSTRCSGTDNEA----------EEIRELVKK 217

  Fly   243 FFDLGVRPSLYRYIPTPTYKKFS---RAMDEIFDTCSMYVNQAIERIDRKSSQGDSNDHKSVLEQ 304
            ..:|..:.|:...:.......||   :.:..:.:...:.|.:.::..:.|:.:.|.. .|.:|:.
plant   218 SLELAGKISVGDVLGPLKVMDFSGNGKKLVAVMEKYDLLVERIMKEREAKAKKKDGT-RKDILDI 281

  Fly   305 LLQIDRKLAVVM----------AMDMLMGGVDTTSTAISGILLNLAKNPEKQQRLREEVLSKLTS 359
            ||:..|.....|          .:|:.|.|.||::.|:...:..|..:|:...:||||:.:.:.|
plant   282 LLETYRDPTAEMKITRNDMKSFLLDVFMAGTDTSAAAMQWAMGQLINHPQAFNKLREEINNVVGS 346

  Fly   360 --LHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYRIPKGTKLLMTNSFLLK 422
              |..|   .|:.:|||||||::|:|||:|......|....|..::|..:...|::|:....:::
plant   347 KRLVKE---SDVPNLPYLRAVLRETLRLHPSAPLIIRECAEDCQVNGCLVKSKTRVLVNVYAIMR 408

  Fly   423 DDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANL 487
            |..|:..|..|||||:|...::...:..|......|.|||||.|.|.|.|..:....|.:.|.:|
plant   409 DSELWADADRFIPERFLESSEEKIGEHQMQFKGQNFRYLPFGSGRRGCPGASLAMNVMHIGVGSL 473

  Fly   488 VRNF 491
            |:.|
plant   474 VQRF 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12c1	NP_001287109.1	p450	45..502	CDD:278495	102/480 (21%)
CYP712A1	NP_181754.1	p450	9..508	CDD:299894	114/524 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000