Protein Alignment Cyp12c1 and cyp27a1.2

DIOPT Version :10

• Sequence 1: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_073769098.1
• Gene: cyp27a1.2 / 795106
• ZFINID: ZDB-GENE-081104-511
• Length: 580
• Species: Danio rerio
• Alignment Length: 526
• Identity: 151/526 - (28%)
• Similarity: 257/526 - (48%)
• Gaps: 56/526 - (10%)

  Fly     9 GLRANSQLAATRNPDASSYVQ------QLESEWEGAKPFTELPGPTRWQ-LFRGFQKGGEYHQLG 66
            |.|:.:..||.    ||..||      :.|::....|.||.|     :| ||:|:.  ...|:|
Zfish    93 GFRSAAGNAAA----ASVSVQDGHRKLKTEADLPEIKIFTML-----YQMLFKGYL--NSVHEL- 145

  Fly    67 MDDVMRLYKKQ-FGDICLIPGLFGMPSTVFTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKD 130
                 :||:|| :|.:..|..  |....:...:||..|::.|.:.::|.||.......:|:.|..
Zfish   146 -----QLYQKQVYGPLWKINA--GNLQGISISSVELLEELLRKDEKYPCRGYMTLWTEHRDLRGI 203

  Fly   131 EFFKNCMGLF-GNGAEWGKNRSAVNPVLMQHRNVAIYLKPMQRVNRQFVNRIREIRD-KESQEVP 193
            .:     |.| ..|.:|.|.|:.:|..::..::...|...:..|...|:.||..:|: ..:.::.
Zfish   204 SY-----GPFTEEGEKWYKLRAVLNKRMLHPKDSVQYGDVVNAVITDFIKRIYYLREMSPTGDLV 263

  Fly   194 GDFMNTINHLTFESVATVALDRELGLLREANPPPEASKLFKNIEVLMDSFFDLGVRPSLYR-YIP 257
            .:..|.:...:.|.:|::..:..:|.| |...|.|..|....|..:......:.:.|:..| |.
Zfish   264 SNLTNELYRFSLEGIASILFETRIGCL-EKEIPAETQKFINFIAQMFTYSMHVALLPNWTRKYF- 326

  Fly   258 TPTYKKFSRAMDEIFDTCSMYVNQAIERIDRK--SSQGDSNDHKSVLEQLLQIDRKLAVVMAMDM 320
             |.::|:....|.||...:..::..:|.|.::  ::|..:.::.:.|....:|.||.......::
Zfish   327 -PFWQKYIDGWDGIFKFGTKMIDMKMEAIQKRVDTNQDVAGEYLTYLLSNGKISRKDVYGSVSEL 390

  Fly   321 LMGGVDTTSTAISGILLNLAKNPEKQQRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRL 385
            |:.|||:||..:...|..|:|:||.|:.|.:|| :|:.......|.|::.|:|:|:|||||:|||
Zfish   391 LLAGVDSTSNTMLWALYLLSKDPEAQETLYQEV-TKVLKDDRIPTAEEVNSMPFLKAVIKETLRL 454

  Fly   386 YPVTFGNAR-SAGADVVLDGYRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDV 449
            |||...|:| .|..:||:..|..||.|...:.:..:.:|::::|..::|.||||||   |.::..
Zfish   455 YPVVPVNSRLIAETEVVIGEYFFPKKTTFTLCHYVISRDEKVFPEPQKFKPERWLR---DGRTRP 516

  Fly   450 LMNKDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHIEYNYSTEKPYKCRF----LYK 510
                  |.|..:|||||.|.|||:||.:|||.|.:|.|::.|.:..: .|....|..|    :|.
Zfish   517 ------NPFGSIPFGFGVRACVGRRIAELEMHLALARLIKLFEMRPD-PTVGEVKANFRSLHMYI 574

  Fly   511 PNIPLK 516
            .|..||
Zfish   575 RNYQLK 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	128/450 (28%)
cyp27a1.2	XP_073769098.1	None