Protein Alignment Cyp12c1 and zgc:136333

DIOPT Version :9

• Sequence 1: NP_001287109.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_009303121.1
• Gene: zgc:136333 / 723999
• ZFINID: ZDB-GENE-060616-143
• Length: 522
• Species: Danio rerio
• Alignment Length: 530
• Identity: 145/530 - (27%)
• Similarity: 255/530 - (48%)
• Gaps: 61/530 - (11%)

  Fly    11 RANSQLAATRNPDASSYVQ------QLESEWEGAKPFTELPGPTRWQ-LFRGFQKGGEYHQLGMD 68
            ||....||     ||..||      :.|::....|.||.|     :| ||:|:.  ...|:|
Zfish    29 RAAGNAAA-----ASVSVQDGHRKLKTEADLPEIKIFTML-----YQMLFKGYL--NSIHEL--- 78

  Fly    69 DVMRLYKKQ-FGDICLIPGLFGMPSTVFTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEF 132
               ::|:|| :|.:..|..  |....:...:||..|::.|.:.::|.||.......:|:.|
Zfish    79 ---QIYQKQVYGPLSKINS--GNLQGISISSVELLEELLRKDEKYPCRGYMTLWTEHRDLR---- 134

  Fly   133 FKNCMGL-FG----NGAEWGKNRSAVNPVLMQHRNVAIYLKPMQRVNRQFVNRIREIRD-KESQE 191
                 |: :|    .|.:|.|.|:.:|..::..::...|...:..|...|:.||..:|: ..:.:
Zfish   135 -----GIGYGPFTEEGEKWYKLRAVLNKRMLHPKDSLQYGDVVNAVITDFIKRIYYLREMSPTGD 194

  Fly   192 VPGDFMNTINHLTFESVATVALDRELGLLREANPPPEASKLFKNIEVLMDSFFDLGVRPSLYR-Y 255
            :..:..|.:...:.|.:|::..:..:|.| |...|.|..:...:|..:......:.:.|:..| |
Zfish   195 LVSNLTNELYRFSLEGIASILFETRIGCL-EKEIPVETQEFINSIAQMFTYSMHVALLPNWTRNY 258

  Fly   256 IPTPTYKKFSRAMDEIFDTCSMYVNQAIERIDRK--SSQGDSNDHKSVLEQLLQIDRKLAVVMAM 318
            .  |.::|:....|.||...:..::..:|.|.::  ::|..:.::.:.|....::..|.......
Zfish   259 F--PFWQKYIDGWDGIFKFGTKMIDMKMEAIQKRVDTNQEVAGEYLTYLLSSGKMSSKDVYGSVS 321

  Fly   319 DMLMGGVDTTSTAISGILLNLAKNPEKQQRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESL 383
            ::|:.||||||..:...|..|:|:|..|:.|.:|| :|:.......|.|::.|:|:|:|||||:|
Zfish   322 ELLLAGVDTTSNTMLWALYLLSKDPAAQETLYQEV-TKVLKDDRIPTAEEVNSMPFLKAVIKETL 385

  Fly   384 RLYPVTFGNAR-SAGADVVLDGYRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKS 447
            |||||...|:| .|..:||:..|..||.|...:.:..:..|::::|..::|.||||||   |.::
Zfish   386 RLYPVVPVNSRLIAETEVVIGEYFFPKKTTFNLCHYAISHDEKVFPEPQKFKPERWLR---DGRT 447

  Fly   448 DVLMNKDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHIEYNYST-EKPYKCRFLYKP 511
            ..      |.|..:|||||.|.|||:||.:|||.|.:|.|::.|.:..:.:. |.....|.:..|
Zfish   448 RP------NPFGSIPFGFGVRACVGRRIAELEMHLALARLIKLFEMRPDPTVGEVKANFRSVLVP 506

  Fly   512 NIPLKFKFTD 521
            |..:...|.:
Zfish   507 NKKVNLHFVE 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12c1	NP_001287109.1	p450	45..502	CDD:278495	128/469 (27%)
zgc:136333	XP_009303121.1	p450	66..505	CDD:278495	128/470 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3547
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	1	0.900	-	-		OOG6_100895
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.780