Protein Alignment Cyp12c1 and Cyp6a22

DIOPT Version :10

• Sequence 1: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 132/497 - (26%)
• Similarity: 206/497 - (41%)
• Gaps: 78/497 - (15%)

  Fly    47 PTRWQL--FRGFQKGGEYHQLGMDDVMRLYKKQFGDICLIPGLFGM--PSTVFTFNVETFEKVYR 107
            |.|:.:  ..||:|...:    :|.|..:|:|..|:.....|.|.|  |..:.| ::|..:::..
  Fly    35 PARFPVGNMEGFRKNKHF----IDIVTPIYEKFKGNGAPFAGFFMMLRPVVLVT-DLELAKQILI 94

  Fly   108 TE-GQWPVRGGAEPVIHYRNKRKDEFFKNCMGLFGNGAEWGKNRSAVNPVLMQHRNVAIYLKP-M 170
            .: ..:..||      .|.|:|.|....:...:  :|.:|...|..::|.....:  ..|:.| :
  Fly    95 QDFANFEDRG------MYHNERDDPLTGHLFRI--DGPKWRPLRQKMSPTFTSAK--MKYMFPTV 149

  Fly   171 QRVNRQFVNRIREIRDKES---QEVPGDFMNTINHLTFESVATVALDRELGLLREANPPPE---- 228
            ..|..:......|:.|...   .|: ||.|   ...|.:.:...|...|...||  ||..|
  Fly   150 CEVGEELTQVCGELADNAMCGILEI-GDLM---ARYTSDVIGRCAFGVECNGLR--NPEAEFAIM 208

  Fly   229 ASKLF------KNIEVLMDSFFDLGVRPSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQAIERID 287
            ..:.|      |.::..::||               |...:|.|......|....||....|.:.
  Fly   209 GRRAFSERRHCKLVDGFIESF---------------PEVARFLRMRQIHQDITDFYVGIVRETVK 258

  Fly   288 RKSSQG-DSNDHKSVLEQL-----LQIDRKLAVVMAMDMLMGGVDTTSTAISGILLNLAKNPEKQ 346
            ::..|| ..:|..::|.::     |.|:...|  .|......|.||:::.:...|..|||.|..|
  Fly   259 QREEQGIVRSDFMNLLIEMKQRGELTIEEMAA--QAFIFFAAGFDTSASTLGFALYELAKQPALQ 321

  Fly   347 QRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYR---IP 408
            .:||||:...|...:.|||.:.|:.|.|:..||.|:||.||:.....|.:.......|.|   |.
  Fly   322 AKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIE 386

  Fly   409 KGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLNAFIYLPFGFGPRMCVGK 473
            .|..||:....:..|..|||...:|||||:|       :|.|..:...|  :||||.|||.|:|.
  Fly   387 PGQMLLIPVYGIHHDPALYPEPHKFIPERFL-------ADQLAQRPTAA--WLPFGDGPRNCIGM 442

  Fly   474 RIVDLEMELTVANLVRNFHIEYNYSTEKPYKCRFLYKPNIPL 515
            |...::..:.:.:|:||||......|:.  |..|| |.||.|
  Fly   443 RFGKMQTTIGLVSLLRNFHFSVCPRTDP--KIEFL-KSNILL 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	124/466 (27%)
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	122/462 (26%)