Protein Alignment Cyp12c1 and cyp27c1

DIOPT Version :10

• Sequence 1: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001011341.1
• Gene: cyp27c1 / 496805
• XenbaseID: XB-GENE-6257635
• Length: 469
• Species: Xenopus tropicalis
• Alignment Length: 498
• Identity: 149/498 - (29%)
• Similarity: 240/498 - (48%)
• Gaps: 51/498 - (10%)

  Fly    44 LPGP-TRWQLFRGFQKGGEYHQLG-MDDVMRLYKKQFGDICLIPGLFGMPSTVFTFNVETFEKVY 106
            :||| |...|...|.:.|    .| :.::.:.:.:|:|.|  ....||....|...:.:...:|.
 Frog     1 MPGPSTMANLVEFFWRDG----FGRIQEIQQKHARQYGRI--FKSHFGPQFVVSIADKDMVAQVL 59

  Fly   107 RTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLF-GNGAEWGKNRSAVNPVLMQHRNVAIYLKPM 170
            |.|...|.|...|....||..|     ....||. ..|.:|...||.:...:::.|:||:|...:
 Frog    60 RAERDAPQRANMESWHEYRELR-----GRSTGLISAEGEKWLNMRSVLRQKILRPRDVAMYSGGV 119

  Fly   171 QRVNRQFVNRIREIRDKESQEVPGDFMNTINHLTF----ESVATVALDRELGLLREANPPPEASK 231
            ..|....|.|||::|.:||.   |..:..:|.|.|    |::||:..:..||.| :...|.:..:
 Frog   120 NEVVEDLVKRIRKLRVQESD---GLTVTNVNDLYFKYSMEAIATILYECRLGCL-DDQIPQQTKE 180

  Fly   232 LFKNIEVLMDSF---FDLGVRPSLYR-YIPTPTYKKFSRAMDEIFDTCSMYVNQAIERIDRKSSQ 292
            ..:.:|::...|   ...|..|...| .||.| :::|.|:.|.:|....::|:..:.:|:.:..:
 Frog   181 YIEALELMFSMFKTTMYAGAIPKWLRPLIPKP-WREFCRSWDGLFKFSQIHVDDRLRQIESQLEK 244

  Fly   293 GDSNDHKSVLEQLL---QIDRKLAVVMAMDMLMGGVDTTSTAISGILLNLAKNPEKQQRLREEVL 354
            |: .....||..||   ::|.:.......:||:.||||||..:|.....|||||..|:.:.::::
 Frog   245 GE-EVQGGVLTHLLLSKELDLEEIYANMTEMLLAGVDTTSFTLSWATYLLAKNPGIQEAVYQQIV 308

  Fly   355 SKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYRIPKGTKLLMTNSF 419
            ... ......|.||:..:|.:|||:||:|||:||..||.|....|:|:.||.|||||:|.:.:..
 Frog   309 QNF-GKDQVPTAEDVPKMPLVRAVVKETLRLFPVLPGNGRVTQDDLVVGGYFIPKGTQLALCHYS 372

  Fly   420 LLKDDRLYPRAKEFIPERWLR-----RKDDDKSDVLMNKDLNAFIYLPFGFGPRMCVGKRIVDLE 479
            ...|...:|.|:||.||||:|     ||::             |..:|||:|.|.|:|:|:.:||
 Frog   373 TSYDAECFPAAEEFRPERWIRSGNLERKEN-------------FGSIPFGYGIRSCIGRRVAELE 424

  Fly   480 MELTVANLVRNFHIEYNYSTEKPY-KCRFLYKPNIPLKFKFTD 521
            |.|.:..|::||.|:.:..|.... |...|..|...:..:|.|
 Frog   425 MHLLLIQLLQNFEIKPSPQTTTVLPKTHGLLCPGGKINVRFVD 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	139/457 (30%)
cyp27c1	NP_001011341.1	cytochrome_P450	30..462	CDD:477761	139/458 (30%)