DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cyp12c1 and Cyp4d14

DIOPT Version :10

Sequence 1:NP_649052.1 Gene:Cyp12c1 / 40037 FlyBaseID:FBgn0036806 Length:524 Species:Drosophila melanogaster
Sequence 2:NP_001259179.1 Gene:Cyp4d14 / 45706 FlyBaseID:FBgn0023541 Length:510 Species:Drosophila melanogaster


Alignment Length:412 Identity:98/412 - (23%)
Similarity:175/412 - (42%) Gaps:97/412 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   135 NCMG---LFGNGAEWGKNRSAVNPVLMQHRNVAIYLKPMQR----VNRQFVNRIREIRDKESQEV 192
            |.:|   |...|.:|.:.|..:.|        |.:.|.::.    .::|....::::.|:     
  Fly   113 NWLGDGLLISQGKKWFRRRKIITP--------AFHFKILEDFVEVFDQQSATMVQKLYDR----- 164

  Fly   193 PGDFMNTINHLTFESVATVALD----RELGLLREANPPPE---------ASKL----FKN----I 236
             .|....||  .|......|:|    ..:|:...|...|:         ||.:    |.|    :
  Fly   165 -ADGKTVIN--MFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRL 226

  Fly   237 EVLMDSFFDLGVRPSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQAIERIDRKSSQGDSNDHKSV 301
            :..|..|:     |.|        ..|.:.|:..:.|..:..:.:..|.:.:..:.|...| .::
  Fly   227 DFTMKLFY-----PKL--------LDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDAD-AAL 277

  Fly   302 LEQLLQIDRKLAVVMAMDMLM-----------------------GGVDTTSTAISGILLNLAKNP 343
            |..:.| .|::|:   :|:|:                       .|.|||:::|:.....||::|
  Fly   278 LNDVGQ-KRRMAL---LDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHP 338

  Fly   344 EKQQRLREEVLSKL-TSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYRI 407
            |.|.|:.:||...: ....:..|::.:..|.||..||||||||:|......|....|.||||..|
  Fly   339 EVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLI 403

  Fly   408 PKGTKLLMTNSFLLKDDRLYPRAKEFIPERW-LRRKDDDKSDVLMNKDLNAFIYLPFGFGPRMCV 471
            |..:.:::......:|...:|..::|||:|: :.||.          :::.|.|.||..|||.|:
  Fly   404 PADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKG----------EISPFAYTPFSAGPRNCI 458

  Fly   472 GKRIVDLEMELTVANLVRNFHI 493
            |::...|||:.|::.:||:|.:
  Fly   459 GQKFAMLEMKSTISKMVRHFEL 480

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp12c1NP_649052.1 CYP24A1-like 76..516 CDD:410677 98/412 (24%)
Cyp4d14NP_001259179.1 CYP4 71..503 CDD:410721 98/412 (24%)

Return to query results.
Submit another query.