Protein Alignment Cyp12c1 and Cyp4ad1

DIOPT Version :10

• Sequence 1: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 108/492 - (21%)
• Similarity: 197/492 - (40%)
• Gaps: 100/492 - (20%)

  Fly    44 LPGPTRW----QLFRGFQKGGEYHQ-----------LGMDDVMRL-YKKQFGDICLIPGLFGMPS 92
            :||||.:    .||:...|..||.:           .|...::.| |.....|...|..:....|
  Fly    35 IPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCRKYDFQGFRSLVFLQYHMMLSDPAEIQNILSSSS 99

  Fly    93 TVFTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLFGNGAEWGKNRSAVNPVL 157
            .::..::.:|.:.:..:|.                           |..:||.|.|::....|.
  Fly   100 LLYKEHLYSFLRPWLGDGL---------------------------LTSSGARWLKHQKLYAPA- 136

  Fly   158 MQHRNVAIYLKPMQRVNRQFVNRIREIRDKESQEVPGDFMNTINHLTFESVATVALDRELGLLRE 222
            .:...:..||:.:.|...|||.::..:.|  :||| .|....:...|.:.|...|..::...|.
  Fly   137 FERSAIEGYLRVVHRTGGQFVQKLDVLSD--TQEV-FDAQELVAKCTLDIVCENATGQDSSSLN- 197

  Fly   223 ANPPPEASKLFKNI----EVLMDSFFDLGVR-PSLYRYIPTPTYKKFSRAMDEIFDTCSMYVNQA 282
                .|.|.|...|    :|:.:..|.:..| .:|:|.  |..|.|..||:..:....:..::|.
  Fly   198 ----GETSDLHGAIKDLCDVVQERTFSIVKRFDALFRL--TSYYMKQRRALSLLRSELNRIISQR 256

  Fly   283 IERIDRKSS-QGDSNDHKSVLEQLL--QIDRKL-----AVVMAMDMLMGGVDTTSTAISGILLNL 339
            ..::..::: |.....:|..|:.||  ::|.|:     .:......:..|.|..:.|||..|..|
  Fly   257 RHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTL 321

  Fly   340 AKNPEKQQRLREEV-------------LSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFG 391
            :::.|.||:..||.             |::|..:|            ||..:|:|:|||||....
  Fly   322 SRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMH------------YLELIIRETLRLYPSVPL 374

  Fly   392 NARSAGADVVLDGYRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLN 456
            .||:....:.::|.::.|.|.::|....:..:::.:.....|.|||:        .:...|..:.
  Fly   375 IARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERF--------ENPTGNVGIE 431

  Fly   457 AFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHI 493
            ||..:||..|||.|:.::....:|:..::.|:|.|.|
  Fly   432 AFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEI 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	96/444 (22%)
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	98/454 (22%)