Protein Alignment Cyp12c1 and Cyp12d1-d

DIOPT Version :10

• Sequence 1: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 208/507 - (41%)
• Similarity: 325/507 - (64%)
• Gaps: 6/507 - (1%)

  Fly    18 ATRNPDASSYVQQLESEWEGAKPFTELPGPTRWQLFRGFQKGGEYHQLGMDDVMRLYKKQFGDIC 82
            ::|:....::.|...|..|..|.:.|:|.|.:::..|.|..|||:....:.:.....:|::|||.
  Fly    19 SSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIY 83

  Fly    83 LIPGLFGMPSTVFTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLFGNGAE-W 146
            ::||:||....|.|||.:..|.|:|.||.||.|.|.:.::::|...:.:.:....||..:..| |
  Fly    84 VMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAW 148

  Fly   147 GKNRSAVNPVLMQHRNVAIYLKPMQRVNRQFVNRIREIRDKESQEVPGDFMNTINHLTFESVATV 211
            ||.|||:||:.||.|.:.:|.:|:..:|.:|:.||:||||.::.|||.||.:.|:.|.|||:..|
  Fly   149 GKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLV 213

  Fly   212 ALDRELGLLREANPPPEASKLFKNIEVLMDSFFDLGVRPSLYRYIPTPTYKKFSRAMDEIFDTCS 276
            |.||::||:|:.....:|..||:....:....|.|.::||:::.|.||||:|..|.:::..:...
  Fly   214 AFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQ 278

  Fly   277 MYVNQAIERIDRKSSQGDSNDHKSVLEQLLQIDRKLAVVMAMDMLMGGVDTTSTAISGILLNLAK 341
            ..:.:..:.::::...|:..:..|:||:|::||.|:||:|::|:|..|||.|:|.:|.:||.|:|
  Fly   279 KMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSK 343

  Fly   342 NPEKQQRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARSAGADVVLDGYR 406
            :|:||.:||||:||.:.:..|....|:||.:|||||||||:||.||..||..|:...||:|.|||
  Fly   344 HPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYR 408

  Fly   407 IPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLNAFIYLPFGFGPRMCV 471
            :||||.:|:.::.|:|:...|||..||:||||||..:..|     ...::.|.:||||||||||:
  Fly   409 VPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGK-----KMQVSPFTFLPFGFGPRMCI 468

  Fly   472 GKRIVDLEMELTVANLVRNFHIEYNYSTEKPYKCRFLYKPNIPLKFKFTDLK 523
            |||:||||||.|||.|:||||:|:|....:|:|..||.:|.|...|||||::
  Fly   469 GKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIE 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	190/440 (43%)
Cyp12d1-d	NP_995812.1	CYP24A1-like	76..515	CDD:410677	190/443 (43%)