DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chmp1 and chmp1b

DIOPT Version :9

Sequence 1:	NP_001287108.1	Gene:	Chmp1 / 40036	FlyBaseID:	FBgn0036805	Length:	203	Species:	Drosophila melanogaster
Sequence 2:	NP_956308.1	Gene:	chmp1b / 336426	ZFINID:	ZDB-GENE-030131-8370	Length:	199	Species:	Danio rerio

Alignment Length:	197	Identity:	147/197 - (74%)
Similarity:	168/197 - (85%)	Gaps:	2/197 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SSMEKHLFNLKFAVKELERNSKKCEKEEKLEKAKAKKAIQKGNMDVARIHAENAIRQKNQAVNYL 68
            |||||||||||||.|||:||||||:||||.||.|.|||||||||:|||||||||||||||:||:|
Zfish     2 SSMEKHLFNLKFAAKELQRNSKKCDKEEKAEKVKVKKAIQKGNMEVARIHAENAIRQKNQSVNFL 66

  Fly    69 RMSARVDAVASRVQSALTTRKVTGSMAGVVKAMDAAMKGMNLEKISSLMEKFESQFEDLDVQSSV 133
            ||||||||||:|||:|:|..:||.|||||||.|||.:|.|||||||.||||||.|||.||||::.
Zfish    67 RMSARVDAVAARVQTAVTMNQVTKSMAGVVKGMDATLKSMNLEKISGLMEKFERQFETLDVQTAQ 131

  Fly   134 MEGTMSDTVTTSVPQGDVDNLLQQVADEAGLELNMELPSGVQSQSVGASTAVSQEQDELTQRLAR 198
            ||.:||.|.|.:.|||.||.|:.::||||||:||||||.| |:.|||.|.| |.|||||:||||:
Zfish   132 MEDSMSSTTTLTTPQGQVDTLMMEMADEAGLDLNMELPQG-QTGSVGTSVA-SAEQDELSQRLAK 194

  Fly   199 LR 200
            ||
Zfish   195 LR 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chmp1	NP_001287108.1	Snf7	42..>167	CDD:419749	90/124 (73%)
chmp1b	NP_956308.1	Snf7	40..189	CDD:304451	108/150 (72%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..199		22/32 (69%)
		MIT-interacting motif	186..196		7/9 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573453
Domainoid	1	1.000	196	1.000	Domainoid score	I3090
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2894
OMA	1	1.010	-	-		QHG53616
OrthoDB	1	1.010	-	-		D1441797at2759
OrthoFinder	1	1.000	-	-		FOG0001910
OrthoInspector	1	1.000	-	-		oto39016
orthoMCL	1	0.900	-	-		OOG6_100996
Panther	1	1.100	-	-	LDO	PTHR10476
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R315
SonicParanoid	1	1.000	-	-		X3097
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.940