DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sgf11 and atxn7l3a

DIOPT Version :9

Sequence 1:	NP_001097638.1	Gene:	Sgf11 / 40035	FlyBaseID:	FBgn0036804	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	NP_001035431.2	Gene:	atxn7l3a / 368510	ZFINID:	ZDB-GENE-030616-253	Length:	367	Species:	Danio rerio

Alignment Length:	166	Identity:	65/166 - (39%)
Similarity:	94/166 - (56%)	Gaps:	16/166 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LDEAANYLYQSLLDDAVVGIFNETHHLRKSGNLAALDGVPEDS--TYRMCEMPNLDIFG-ISTAK 101
            |:..|:.:|..|::||.:|:..|.|...|.|.. .||...::|  .:.:.:.|.:|||| :....
Zfish    16 LEALAHDVYSDLVEDACLGLCFEVHRAVKQGYF-FLDETDQESMKDFEIVDQPGVDIFGQVYNQW 79

  Fly   102 KPMDCTCPNCDRLVAAARFAPHLEKCMGMGRISSRIASRRLATKEGATSAHLHSSGNTGGTDDED 166
            |..:|.||||.|.:||:|||||||||:||||.|||||:||:|:....:.:......|    ||.:
Zfish    80 KNKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRIASSNNTSKSESDQEDN----DDIN 140

  Fly   167 DVDWS------SDKRRKKSNQNS--RNNGSKKNNGK 194
            |.|||      :.||:.:.|.||  |:...|..||:
Zfish   141 DNDWSYGSEKKAKKRKSEKNPNSPRRSKSLKHKNGE 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgf11	NP_001097638.1	Sgf11	102..134	CDD:285427	22/31 (71%)
atxn7l3a	NP_001035431.2	Sgf11	80..112	CDD:285427	22/31 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..184		20/65 (31%)
		SCA7	<211..>240	CDD:285508
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10998
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003043
OrthoInspector	1	1.000	-	-		otm25515
orthoMCL	1	0.900	-	-		OOG6_104688
Panther	1	1.100	-	-	LDO	PTHR46367
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4754
SonicParanoid	1	1.000	-	-		X5479
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.900