DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GNBP1 and UTR2

DIOPT Version :9

Sequence 1:	NP_524142.2	Gene:	GNBP1 / 40034	FlyBaseID:	FBgn0040323	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_010874.3	Gene:	UTR2 / 856671	SGDID:	S000000766	Length:	467	Species:	Saccharomyces cerevisiae

Alignment Length:	265	Identity:	49/265 - (18%)
Similarity:	84/265 - (31%)	Gaps:	100/265 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 LSIANS-------------RLDLSERCTGTH---------NRIKECILHSTGSGP---------- 264
            ::|.||             |::.:..|..|.         ::..||     |:|.
Yeast     1 MAIVNSWLICLVSIFSFVVRVEAATFCNATQACPEDKPCCSQYGEC-----GTGQYCLNNCDVRY 60

  Fly   265 ----SGIMPPIVTPRISTK-ETFAFQYGRIE-IRAKLPKGDWIV-----------PLLLLEPLTE 312
                ...||..:....||| :.::.:.|... ....:.:.||:.           .|:|..|...
Yeast    61 SFSHDSCMPVPICKSSSTKFKDYSSKLGNANTFLGNVSEADWLYTGDVLDYDDEESLILAMPKNS 125

  Fly   313 -----------WYGQSGYESGQLRVALARGNSVLRMPRGKLVDGRSLYGGPVLSTD--------- 357
                       |||:   .|.:::.:...|          :|.|..||.|.....|
Yeast   126 GGTVLSSTRAVWYGK---VSARIKTSHLAG----------VVTGFILYSGAGDELDYEFVGADLE 177

  Fly   358 AHQREDLWLSKRKISHFG--------DDFHTYSLDWSSNRLLFSVDGQV-----YGEMLNGFTEL 409
            ..|....|.|....::..        :::|||.|||..:.:.:|:||.|     ..|..|..|:.
Yeast   178 TAQTNFYWESVLNYTNSANISTTDTFENYHTYELDWHEDYVTWSIDGVVGRTLYKNETYNATTQK 242

  Fly   410 DENPR 414
            .:.|:
Yeast   243 YQYPQ 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GNBP1	NP_524142.2	CBM39	21..126	CDD:292510
GNBP1	NP_524142.2	GH16_beta_GRP	175..491	CDD:185688	49/265 (18%)
UTR2	NP_010874.3	ChtBD1_GH16	25..71	CDD:211314	8/50 (16%)
UTR2	NP_010874.3	GH16_fungal_CRH1_transglycosylase	91..302	CDD:185692	33/170 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345594
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930