DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MYPT-75D and AT1G05640

DIOPT Version :9

Sequence 1:	NP_001262018.1	Gene:	MYPT-75D / 40032	FlyBaseID:	FBgn0036801	Length:	741	Species:	Drosophila melanogaster
Sequence 2:	NP_172055.1	Gene:	AT1G05640 / 837070	AraportID:	AT1G05640	Length:	627	Species:	Arabidopsis thaliana

Alignment Length:	366	Identity:	91/366 - (24%)
Similarity:	149/366 - (40%)	Gaps:	62/366 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 QRAKGNTASGGSGTGSLGNGLMNGN-GDTTHHFRHANG---SGTLSGRRHISFENSVVLLEAASR 129
            :|.|...:.|..|...|......|| |......|..||   ...||.::::  |....|..||..
plant   101 ERKKKTDSPGKRGDSPLHLAARTGNLGKVMELIRACNGIEELKELSSKQNL--EGETPLYSAAEN 163

  Fly   130 NDMPEVAALLQHGITPDAAN---EDGLTAMHQACIDNNVEMLQLLLEYGANVD-AQDSDKWTPLH 190
            .....|..:|:| :..|.|:   .:|....|.|....::|.|:.|||...|:. ..|....|.||
plant   164 GHSLVVEEMLKH-MDLDTASVKARNGFDPFHVAAKQGHIEALKKLLETFPNLAMTVDLSCTTALH 227

  Fly   191 AAATCGHLELVRILIRHGANLLAVNTDGNMPYDLCDDEKTLDFIEGEMAQRGVTQELIDE----- 250
            .||:.||.::|.:|::         ||.::.....::.||.......|..|.|.:.||..
plant   228 TAASQGHTDVVNLLLK---------TDSHLAKIAKNNGKTALHSAARMGHREVVKSLIGNDASIG 283

  Fly   251 --------------TRSSTERIMLRDLMELARTG-GDLEEPDYQCATPLHIAAANGYVRVVEFLL 300
                          .:...|.|:|    ||.:.. ..|...|.:..||||.|...|.:::|..|:
plant   284 FRTDKKGQTALHMAVKGQNEGIVL----ELVKPDPAILSVEDSKGNTPLHTATNKGRIKIVRCLV 344

  Fly   301 E-QHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADLNVRNKDDETPSDICEDPEIRERIEQ 364
            . ..:|::||:|...|.:..|...|:.|::.:|.:.||   ...||...|.:..:  ::.:.:..
plant   345 SFDGINLNAMNKAGDTALDIAEKIGNPELVSVLKEAGA---ATAKDLGKPRNPAK--QLNQTVSD 404

  Fly   365 LKTEQESKRLAEAQRRRVRRSQSNNTRAQSVRRTSLRDKTL 405
            :|.|.:| :|.::::..||           |||.:.|.|.|
plant   405 IKHEVQS-QLQQSRQTGVR-----------VRRIAKRLKKL 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MYPT-75D	NP_001262018.1	Ank_2	123..215	CDD:289560	27/95 (28%)
		ANK repeat	123..149	CDD:293786	7/25 (28%)
		ANK	146..332	CDD:238125	53/210 (25%)
		ANK repeat	151..182	CDD:293786	9/31 (29%)
		ANK repeat	184..215	CDD:293786	9/30 (30%)
		ANK repeat	217..310	CDD:293786	25/113 (22%)
		Ank_4	282..332	CDD:290365	16/50 (32%)
		ANK repeat	312..343	CDD:293786	7/30 (23%)
		Ank_4	314..>353	CDD:290365	10/38 (26%)
AT1G05640	NP_172055.1	ANK repeat	112..150	CDD:293786	10/37 (27%)
		Ank_2	117..209	CDD:403870	24/94 (26%)
		ANK repeat	152..185	CDD:293786	9/33 (27%)
		ANK repeat	187..219	CDD:293786	9/31 (29%)
		ANKYR	191..413	CDD:223738	59/240 (25%)
		Ank_2	192..285	CDD:403870	27/101 (27%)
		ANK repeat	221..253	CDD:293786	11/40 (28%)
		ANK repeat	255..287	CDD:293786	7/31 (23%)
		ANK repeat	289..321	CDD:293786	6/35 (17%)
		ANK repeat	323..355	CDD:293786	10/31 (32%)
		PGG	435..550	CDD:404788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24186
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100