DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MYPT-75D and AT2G01680

DIOPT Version :9

Sequence 1:	NP_001262018.1	Gene:	MYPT-75D / 40032	FlyBaseID:	FBgn0036801	Length:	741	Species:	Drosophila melanogaster
Sequence 2:	NP_565274.1	Gene:	AT2G01680 / 814697	AraportID:	AT2G01680	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	401	Identity:	79/401 - (19%)
Similarity:	136/401 - (33%)	Gaps:	126/401 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 NEDGLTAMHQACIDNNVEMLQLLLEYGA--NVDAQDSDKWTPLHAAATCGHLELVRILIRHGANL 211
            |:.|.||::.:..:|..::.:.|:.:.:  .|..:........|.||..|||.:|:.|:|....|
plant    56 NDAGETAVYISAAENLEDIFRYLIRFSSLETVKIRSKSDMNAFHVAAKRGHLGIVKELLRLWPEL 120

  Fly   212 LAVNTDGNMPYDLCDDEKTLDFIEGEMAQRGVTQELIDETRSSTERIMLRDLMELARTGGDLEEP 276
            ..:          ||...|                      |......::|.:|:.....|:
plant   121 CRI----------CDASNT----------------------SPLYAAAVQDHLEIVNAMLDV--- 150

  Fly   277 DYQCA--------TPLHIAAANGYVRVVEFLLEQHVN-VDAMDKDLWTPVHAAACWGHLEVLEML 332
            |..||        |.||.|...|.:|:|:.|:|:... |...||...|.:|.|.....|||:|.:
plant   151 DPSCAMIVRKNGKTSLHTAGRYGLLRIVKALIEKDAAIVGVKDKKGQTALHMAVKGRSLEVVEEI 215

  Fly   333 AQCGADLNVRNKDDETPSDICEDPEIRERIEQLKTEQESKRLAEAQRRRVRRSQSNNTRAQ-SVR 396
            .|  ||..:.|:                                       |.:..||... :.|
plant   216 LQ--ADYTILNE---------------------------------------RDRKGNTALHIATR 239

  Fly   397 RTSLRDKTLTTKKDAVEETRLRLQAQEATD-------SEAPSSAGDPLTNGYGYGNNNGEKRPST 454
            :...:..:|.....|:|...:..|.:.|.|       ||:.....:.|.              ..
plant   240 KARPQITSLLLTFTAIEVNAINNQKETAMDLADKLQYSESALEINEALV--------------EA 290

  Fly   455 GSSNGQPLPHSKSADALDNATAALSANATHSYPSRRPPDGRENDELLRLKAAGAAGEM------- 512
            |:.:|:.:.....|.||..|.:.:.    |...|:.    .:|::..| :.:|.|.|:
plant   291 GAKHGRFIGREDEARALKRAVSDIK----HEVQSQL----LQNEKTNR-RVSGIAKELRKLHREA 346

  Fly   513 -QRATSAAAVI 522
             |..|::..|:
plant   347 VQNTTNSITVV 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MYPT-75D	NP_001262018.1	Ank_2	123..215	CDD:289560	17/67 (25%)
		ANK repeat	123..149	CDD:293786	79/401 (20%)
		ANK	146..332	CDD:238125	46/193 (24%)
		ANK repeat	151..182	CDD:293786	6/32 (19%)
		ANK repeat	184..215	CDD:293786	10/30 (33%)
		ANK repeat	217..310	CDD:293786	20/101 (20%)
		Ank_4	282..332	CDD:290365	19/50 (38%)
		ANK repeat	312..343	CDD:293786	10/30 (33%)
		Ank_4	314..>353	CDD:290365	11/38 (29%)
AT2G01680	NP_565274.1	Ank_2	<52..114	CDD:403870	14/57 (25%)
		ANK repeat	59..91	CDD:293786	6/31 (19%)
		ANK repeat	97..125	CDD:293786	10/37 (27%)
		Ank_2	98..186	CDD:403870	29/122 (24%)
		ANK repeat	127..156	CDD:293786	7/53 (13%)
		ANK repeat	161..193	CDD:293786	10/31 (32%)
		Ank_2	166..250	CDD:403870	27/124 (22%)
		ANK repeat	195..227	CDD:293786	11/72 (15%)
		ANK repeat	229..261	CDD:293786	6/31 (19%)
		PGG	345..455	CDD:404788	3/13 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24186
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100