Protein Alignment MYPT-75D and ppp1r16a

DIOPT Version :9

• Sequence 1: NP_001262018.1
• Gene: MYPT-75D / 40032
• FlyBaseID: FBgn0036801
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001072353.1
• Gene: ppp1r16a / 779806
• XenbaseID: XB-GENE-5762924
• Length: 549
• Species: Xenopus tropicalis
• Alignment Length: 525
• Identity: 208/525 - (39%)
• Similarity: 298/525 - (56%)
• Gaps: 70/525 - (13%)

  Fly    24 EHADLVAEMQTVESLPTHERLQLARLRRAQQLKLSRQKDKEWAKLQRAKGNTASGGSGTGSLGNG 88
            ||.:|::||..|..:.|.|||:.|:.||||||       |:||:.::         .|.|....|
 Frog     3 EHMELLSEMPAVSRMTTQERLKHAQKRRAQQL-------KKWAQFEK---------DGQGKKAKG 51

  Fly    89 LMNGNGDTTHHFRHANGSGTLSGRRHISFENSVVLLEAASRNDMPEVAALLQHGITPDAANEDGL 153
            .....|.              ...|.:.|..:|.|||||:|||:.||..|||:|.:|:..|||||
 Frog    52 RQKKQGS--------------KEERRVMFPQNVTLLEAAARNDIEEVRHLLQNGFSPNLYNEDGL 102

  Fly   154 TAMHQACIDNNVEMLQLLLEYGANVDAQDSDKWTPLHAAATCGHLELVRILIRHGANLLAVNTDG 218
            ||:||.|||:..|::::|:..||:|:|.||:.|||||||||||||.||.:||:|||||||||:||
 Frog   103 TALHQCCIDDYEEIVRMLIGAGADVNACDSELWTPLHAAATCGHLHLVELLIKHGANLLAVNSDG 167

  Fly   219 NMPYDLCDDEKTLDFIEGEMAQRGVTQELIDETRSSTERIMLRDLMELARTGGDLEEPDYQCATP 283
            |||||||:|:.|||.||..||::|:|||.|:|.|.:||:.||.|:..|..|||::...:....:.
 Frog   168 NMPYDLCEDDVTLDHIETAMAEQGITQEKIEECRGATEQHMLEDIQHLVETGGEVNAHNPHGTSL 232

  Fly   284 LHIAAANGYVRVVEFLLEQHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADLNVRNKDDET 348
            |||||||||:...|.|||....|:|.|:|.|.|:|||||||.:.|:|:|...|||||.:::.|||
 Frog   233 LHIAAANGYLATAELLLEHKAQVNARDQDGWEPLHAAACWGQIHVVELLVAHGADLNSKSQLDET 297

  Fly   349 PSDICEDPEIRERIEQLKTEQESKRLAEAQRRRV--RRSQSNNTRAQSVRRTSLRDKTLTTKKDA 411
            |.|:|.|.|:|.:|.:||.:.|:.|.::.:.|..  ||:.|..:|.:.|||.|:.::|...:::.
 Frog   298 PLDVCGDEEVRAKILELKHKHEAIRKSQDKHRTALQRRTSSAGSRGKVVRRVSVTERTNMYRREH 362

  Fly   412 VEETRLRLQ--------------AQEATDSE----APSSAGDPLTNGYGYGNNNGEKRPSTGSS- 457
            .:|..:..|              ..:.|::|    .||:..:|    .....|.|::.|:.||.
 Frog   363 QKEAMVWQQRGSRENEVEQQDEDEDKTTNTEMQQHQPSAEAEP----EKAARNEGDEGPAEGSDV 423

  Fly   458 -----------NGQPLPHSKS--ADALDNATAALSANATHSYPSRRPPDGRENDELLRLKAAGAA 509
                       ||..:|.||.  :..||.:.:...|....:.|..  .:.|.:..|..||...||
 Frog   424 PVSSSLQSFHRNGSLVPASKHTFSKRLDRSVSYQLATQGDTGPDL--SNERSHHTLAELKRQRAA 486

  Fly   510 GEMQR 514
            .::||
 Frog   487 AKLQR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYPT-75D	NP_001262018.1	Ank_2	123..215	CDD:289560	59/91 (65%)
		ANK repeat	123..149	CDD:293786	15/25 (60%)
		ANK	146..332	CDD:238125	107/185 (58%)
		ANK repeat	151..182	CDD:293786	16/30 (53%)
		ANK repeat	184..215	CDD:293786	24/30 (80%)
		ANK repeat	217..310	CDD:293786	48/92 (52%)
		Ank_4	282..332	CDD:290365	28/49 (57%)
		ANK repeat	312..343	CDD:293786	18/30 (60%)
		Ank_4	314..>353	CDD:290365	22/38 (58%)
ppp1r16a	NP_001072353.1	ANK repeat	72..98	CDD:293786	15/25 (60%)
		ANK	95..282	CDD:238125	107/186 (58%)
		ANK repeat	100..131	CDD:293786	16/30 (53%)
		ANK repeat	133..164	CDD:293786	24/30 (80%)
		ANK	223..332	CDD:238125	49/108 (45%)
		ANK repeat	228..259	CDD:293786	15/30 (50%)
		ANK repeat	261..289	CDD:293786	16/27 (59%)
		GREB1	<328..>530	CDD:318077	39/170 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9557
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2273
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D258197at33208
OrthoFinder	1	1.000	-	-		FOG0003042
OrthoInspector	1	1.000	-	-		otm47772
Panther	1	1.100	-	-	LDO	PTHR24186
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2029
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070