Protein Alignment MYPT-75D and zmp:0000001167

DIOPT Version :10

• Sequence 1: NP_649049.1
• Gene: MYPT-75D / 40032
• FlyBaseID: FBgn0036801
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_002666820.3
• Gene: zmp:0000001167 / 571837
• ZFINID: ZDB-GENE-140106-127
• Length: 889
• Species: Danio rerio
• Alignment Length: 831
• Identity: 205/831 - (24%)
• Similarity: 337/831 - (40%)
• Gaps: 228/831 - (27%)

  Fly    43 RLQLARLRRAQQLKLSRQKDKEWAKLQRAKGNTASGGSGTGSLGNGLMNGNGDTTHHFRHANGSG 107
            |.:.|:.||..||       :.|.            ||.|...|              ..|....
Zfish     8 RSEAAKQRRQDQL-------QRWQ------------GSETDRTG--------------AEARSHS 39

  Fly   108 TLSGRR--HISFENSVVLLEAASRNDMPEVAALLQHGITPDAANEDGLTAMHQACIDNNVEMLQL 170
            ...|.|  .:.|....|.:.|.|..|..|||.||:.|...:.||.|||||:||||||.|.||:|.
Zfish    40 VAPGHRRARVRFAQGAVFMAACSAGDREEVAELLRQGADINHANIDGLTALHQACIDENAEMVQF 104

  Fly   171 LLEYGANVDAQDSDKWTPLHAAATCGHLELVRILIRHGANLLAVNTDGNMPYDLCDDEKTLDFIE 235
            |:|.|:.|:..|::.||||||||:||.:::.:.||.|||::.|||::|.:|.|:..::.....::
Zfish   105 LVENGSEVNRGDNEGWTPLHAAASCGFIQITKYLIEHGAHVGAVNSEGELPLDVATEDAMNRLLK 169

  Fly   236 GEMAQRGVTQELIDETRSSTERIMLRDLME-LARTGGDLEEPDYQCATPLHIAAANGYVRVVEFL 299
            .|:.::|:.   :|:.|...||:||:|.|. ||.:|..:..|:.| ||.||:|||.||:.|::.|
Zfish   170 AEVKKQGID---VDQARREEERVMLQDAMTVLAGSGSLVPHPNTQ-ATALHVAAAKGYIEVLKVL 230

  Fly   300 LEQHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADLNVRNKDDETPSDICEDPEIRERIEQ 364
            |:..::||:.|.|.||..||||.||..|...:||:...|:...|...:||.|:. |..|.:.:|:
Zfish   231 LKCGIDVDSRDSDGWTAFHAAAHWGQEEACSLLAEHMCDMTAVNNVGQTPLDVA-DENIIDNLEE 294

  Fly   365 LKTEQESKRLAEAQRRRVRRSQSN--------NTRAQSVRRTSLRDK---------------TLT 406
            |:.:|.:.| :|.|:.:....:::        ..|..|:.|.|.|:|               ||.
Zfish   295 LQKKQNAMR-SEKQKIQTPVIETSPPVSMAPARPRRTSISRMSSREKITLHGREKHAPPTLQTLP 358

  Fly   407 TKKDAVEETRLRLQAQEAT------DSEAPSSA-------------------GDPLTNGYGYGNN 446
            |::|..|.||...|::.::      :||:.|.|                   ..|:|:.......
Zfish   359 TEEDEDESTRTASQSKPSSSSSSEEESESESDAESEKAKTREMINNLNNKRNAAPVTSSVTSSGP 423

  Fly   447 NGEKRP----------------------------STGSSNG------------------------ 459
            |..|:.                            |||:|:.
Zfish   424 NQVKKTEAGRTPVTEAPGSWRTSLRKAGSSVTLGSTGASDAASEALKDPETKLGMTRSASSPRLS 488

  Fly   460 -------------QPLPH------SKSADALDNATAALSANATHSYPSRRPPDGRENDELLRLKA 505
                         ||.|.      |.::...||.::.||.::  ||..|.......:.....|..
Zfish   489 SEADNKEPRLARVQPTPSRRLFSISDNSTNSDNTSSLLSRSS--SYTRRLNTQSASDASNPSLPR 551

  Fly   506 AGAAGEMQRATSAAAVILTEKGTAASAEAVQIQSSKEAANGKINVQVTVLVDTNSTHHHQQHQQ- 569
            :.:.|.....:|..:|.....|.:.....|..:|::|.|..|..|..:|...|.:|...:..|:
Zfish   552 SSSYGRKLDESSVTSVNSATSGLSRLNNLVAQRSAQEEAEKKDPVSNSVTTTTTTTGESETKQRR 616

  Fly   570 --------------QQQQQQQHHHQ-----QHVLL--LQQHQQLQQHQ----QQQQQQQQQQHVA 609
                          |::.:.:|..|     |.|.|  ||:.::..:.:    ::.::::.:|...
Zfish   617 KSYLTPVRDEEAEAQRKARSRHARQSRRSTQGVTLTDLQEAEKTMKTENKGKKEDEEKEGKQKKG 681

  Fly   610 LDG---YSATLANLKKQRSLSRTANVLNTFELSSQTASNAHPIAAANATTTNGSVLGA------- 664
            .:|   :.:.:|||:|...|..|                 ||..|......:...:.|
Zfish   682 EEGEVSWRSRIANLQKSDLLGLT-----------------HPPGAPRPDRPDADSIVADIEERMR 729

  Fly   665 ----------GGSSSNNNNNLSTSNNNNNGSAPISTQPTLGHMGAGSVLSD 705
                      |.:..:::|..|....::.|..|.:.:.|...  |.|:|:|
Zfish   730 ERRRTRARRRGKTGESDDNEPSGEEESSGGREPQTDRHTSSR--ADSLLND 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYPT-75D	NP_649049.1	ANKYR	123..366	CDD:440430	102/243 (42%)
		ANK repeat	123..149	CDD:293786	9/25 (36%)
		ANK repeat	151..182	CDD:293786	19/30 (63%)
		ANK repeat	184..215	CDD:293786	16/30 (53%)
		ANK repeat	217..310	CDD:293786	32/93 (34%)
		Ank_4	<259..300	CDD:372654	19/41 (46%)
		ANK repeat	312..343	CDD:293786	13/30 (43%)
zmp:0000001167	XP_002666820.3	None