DRSC/TRiP Functional Genomics Resources

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Protein Alignment MYPT-75D and NFKBIE

DIOPT Version :9

Sequence 1:NP_001262018.1 Gene:MYPT-75D / 40032 FlyBaseID:FBgn0036801 Length:741 Species:Drosophila melanogaster
Sequence 2:NP_004547.3 Gene:NFKBIE / 4794 HGNCID:7799 Length:361 Species:Homo sapiens


Alignment Length:331 Identity:86/331 - (25%)
Similarity:126/331 - (38%) Gaps:62/331 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 KEWAKLQRAKGNTASGGSGTGSLGNGLMNGNGDTTHH------FRHANGSGTLSGRR-----HIS 116
            ||..:.:.|.|..|....|:.||...|....|.....      ..|.   |.||.::     :||
Human    56 KEPQEKEDADGERADSTYGSSSLTYTLSLLGGPEAEDPAPRLPLPHV---GALSPQQLEALTYIS 117

  Fly   117 FENSVVLLEAASRNDMPEV----AALLQHGITPDAANEDGLTAMHQACIDNNVEMLQLLLEYGAN 177
             |:...|:..|..::.|.|    .|||...:. |..|....||:|.|...:....::.|:..||:
Human   118 -EDGDTLVHLAVIHEAPAVLLCCLALLPQEVL-DIQNNLYQTALHLAVHLDQPGAVRALVLKGAS 180

  Fly   178 VDAQDSDKWTPLHAAATCGHLELVRILIR----------HGANLLAVNTDGNMPYDLCDDEKTLD 232
            ...||....|.||.|....||...|.|:.          |..:|...|..|.....:...:|.  
Human   181 RALQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGTSHSLDLQLQNWQGLACLHIATLQKN-- 243

  Fly   233 FIEGEMAQRGVTQELIDETRSSTERIMLRDLME-LARTGGDLE-EPDYQCATPLHIAAANGYVRV 295
                                        :.||| |.|.|.|:: :......|.||:|.......:
Human   244 ----------------------------QPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGL 280

  Fly   296 VEFLLEQHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADLNVRNKDDETPSDICEDPEIRE 360
            |:|||:....|||...:..||:|.||..|.:.:...|.:.|||..:||.:||||.|:.|:..:..
Human   281 VQFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLTEESLVLL 345

  Fly   361 RIEQLK 366
            ..:.||
Human   346 PFDDLK 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MYPT-75DNP_001262018.1 Ank_2 123..215 CDD:289560 28/105 (27%)
ANK repeat 123..149 CDD:293786 8/29 (28%)
ANK 146..332 CDD:238125 48/197 (24%)
ANK repeat 151..182 CDD:293786 7/30 (23%)
ANK repeat 184..215 CDD:293786 10/40 (25%)
ANK repeat 217..310 CDD:293786 20/94 (21%)
Ank_4 282..332 CDD:290365 17/49 (35%)
ANK repeat 312..343 CDD:293786 10/30 (33%)
Ank_4 314..>353 CDD:290365 17/38 (45%)
NFKBIENP_004547.3 ANK repeat 119..152 CDD:293786 8/33 (24%)
Ank_2 <149..209 CDD:372319 19/59 (32%)
ANK repeat 154..185 CDD:293786 7/30 (23%)
ANKYR <182..328 CDD:223738 43/175 (25%)
ANK repeat 187..228 CDD:293786 10/40 (25%)
ANK repeat 231..261 CDD:293786 9/59 (15%)
ANK repeat 264..295 CDD:293786 11/30 (37%)
ANK repeat 297..328 CDD:293786 10/30 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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