DRSC/TRiP Functional Genomics Resources

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Protein Alignment MYPT-75D and Nfkbie

DIOPT Version :9

Sequence 1:NP_001262018.1 Gene:MYPT-75D / 40032 FlyBaseID:FBgn0036801 Length:741 Species:Drosophila melanogaster
Sequence 2:NP_001291885.1 Gene:Nfkbie / 18037 MGIID:1194908 Length:371 Species:Mus musculus


Alignment Length:341 Identity:84/341 - (24%)
Similarity:120/341 - (35%) Gaps:90/341 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 TASGGSGTGSLGNGLMNGNGDTTH---HFRHANGSGTLSGRRHISFENSVVLLEAASRND----- 131
            ||:.|||:...|......:...||   ....|:|....|.....|...|..|||.....|     
Mouse    33 TAAPGSGSSQSGCPQPWRHAPETHKEPEKEDADGERADSTYASSSLTESFPLLERPEAKDPSPPA 97

  Fly   132 ----MPEVAALLQHGITPDA------ANEDGLTAMHQACIDNNVEMLQLLLEYGAN--VDAQDSD 184
                :|....|     :|..      .:|||.|.:|.|.|.....:|...|.:...  :|.|::.
Mouse    98 PGSPLPPAGVL-----SPQQLEALTYISEDGDTLLHLAVIHEAPSVLFCCLAFLPQEVLDIQNNL 157

  Fly   185 KWTPLHAAATCGHLELVRILIRHGANLLAVNTDGNM----------------------------- 220
            ..|.||.|......::||.|:..||:.:..:..|:.                             
Mouse   158 YQTALHLAVHLDQPDVVRALVLKGASRILQDQHGDTALHVACRRQNLACACCLLEEQPEPGRQLS 222

  Fly   221 -PYDL---------CDDEKTLDFIEGEMAQRGVTQELIDETRSSTERIMLRDLMELARTGGDLE- 274
             |.||         |....||        ||  .|.||:               .|.:.|.|:: 
Mouse   223 HPLDLQLKNWQGLACLHIATL--------QR--NQPLIE---------------LLLQNGADIDV 262

  Fly   275 EPDYQCATPLHIAAANGYVRVVEFLLEQHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADL 339
            :......|.||:|.......:|:|||:....|||...:..||:|.||..|...:...|.:.|||.
Mouse   263 QEGTSGKTALHLAVETQERSLVQFLLQAGARVDARMLNGCTPLHLAAGRGLNSISSTLCEAGADS 327

  Fly   340 NVRNKDDETPSDICED 355
            .:.|.:||||.|:.||
Mouse   328 LLLNVEDETPQDLAED 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MYPT-75DNP_001262018.1 Ank_2 123..215 CDD:289560 27/108 (25%)
ANK repeat 123..149 CDD:293786 7/40 (18%)
ANK 146..332 CDD:238125 52/233 (22%)
ANK repeat 151..182 CDD:293786 9/32 (28%)
ANK repeat 184..215 CDD:293786 9/30 (30%)
ANK repeat 217..310 CDD:293786 26/132 (20%)
Ank_4 282..332 CDD:290365 17/49 (35%)
ANK repeat 312..343 CDD:293786 10/30 (33%)
Ank_4 314..>353 CDD:290365 16/38 (42%)
NfkbieNP_001291885.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..108 18/74 (24%)
Ank_2 <116..188 CDD:289560 20/71 (28%)
ANK 118..254 CDD:238125 32/160 (20%)
ANK repeat 122..155 CDD:293786 9/32 (28%)
ANK 1 122..155 9/32 (28%)
ANK 152..320 CDD:238125 43/192 (22%)
ANK 2 157..186 9/28 (32%)
ANK repeat 159..188 CDD:293786 9/28 (32%)
Ank_2 162..263 CDD:289560 23/125 (18%)
ANK repeat 190..231 CDD:293786 4/40 (10%)
ANK 3 190..219 1/28 (4%)
ANK 4 233..262 11/53 (21%)
ANK repeat 234..264 CDD:293786 11/54 (20%)
Ank_2 238..326 CDD:289560 29/112 (26%)
ANK repeat 267..298 CDD:293786 11/30 (37%)
ANK 5 267..296 9/28 (32%)
ANK 295..>370 CDD:238125 20/49 (41%)
ANK repeat 300..334 CDD:293786 11/33 (33%)
ANK 6 300..329 10/28 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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