Protein Alignment MYPT-75D and Mbs

DIOPT Version :10

• Sequence 1: NP_649049.1
• Gene: MYPT-75D / 40032
• FlyBaseID: FBgn0036801
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_061505057.1
• Gene: Mbs / 1277253
• VectorBaseID: AGAMI1_011888
• Length: 1766
• Species: Anopheles gambiae
• Alignment Length: 812
• Identity: 195/812 - (24%)
• Similarity: 314/812 - (38%)
• Gaps: 225/812 - (27%)

  Fly    47 ARLRRAQQLKLSRQKDKEWAKLQRAKGNTASGGSGTGSLGNGLMNGNGDTTHHFRHANGSGTLSG 111
            |:.:||:||       |.|.:.:                    ||         :..:|:.....
Mosquito    10 AQYKRAEQL-------KRWEESE--------------------MN---------KKLSGAPKSPS 38

  Fly   112 RRHISFENSVVLLEAASRNDMPEVAALLQHGITPDAANEDGLTAMHQACIDNNVEMLQLLLEYGA 176
            .|.|.|.:..:.|.|....|..||..||::|...|.||.|||||:||||||:|::|::.|::.||
Mosquito    39 SRRIKFSSGCIFLAACVAGDKEEVEWLLKNGADIDTANVDGLTALHQACIDDNLDMVEFLVQKGA 103

  Fly   177 NVDAQDSDKWTPLHAAATCGHLELVRILIRHGANLLAVNTDGNMPYDLCDDEKTLDFIEGEMAQR 241
            :|:.:|::.||||||.|:||.|.:.|.||.:||:|.::|:||.:..||.:.:...|.|:..:.::
Mosquito   104 DVNRKDNEGWTPLHATASCGFLSIARYLIENGADLASINSDGELAVDLANSDAMEDLIQHHLDEQ 168

  Fly   242 GVTQELIDETRSSTERIMLRDLMELARTGGDLEEPDYQC--------ATPLHIAAANGYVRVVEF 298
            |:..|   |.|.:.|||||.|..:..||    :.||  |        ||.:|:|||.||:.|::.
Mosquito   169 GIDCE---EARQAEERIMLSDATKWLRT----DSPD--CDKAHPKTGATAIHVAAAKGYIGVLKL 224

  Fly   299 LLEQHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADLNVRNKDDETPSDICEDPEIRERIE 363
            |||...::|..|.|.|||:||||.||..|..:||....||::|:|...:...||.:|..:....:
Mosquito   225 LLEGRGDIDRQDVDGWTPLHAAAYWGQKEATQMLLNASADIDVQNYSGQLAIDIAQDDIVPLLKD 289

  Fly   364 QLKTEQESKRLAEAQRRRVRRSQSNNTRAQSVRRTSLRDKTLTTKKDAVEETRLRLQAQEATDSE 428
            ..|..:.:||...:...|:..:..|:|..             .||...||        .:..||.
Mosquito   290 ARKNGKRTKRRPPSHGNRITDNFENSTET-------------PTKVIRVE--------VKPIDSN 333

  Fly   429 APSSAGDPLTNGYGYGNNNGEKRPSTGSSNGQPLPHSKSA-----------------------DA 470
            ....||..:...||..::.||       :..:.||.|...                       |.
Mosquito   334 KEKEAGGSVAVDYGDDDDGGE-------NVAEALPESPQVAGDQEEEEAADEKDEEEDEETMDDT 391

  Fly   471 LDNA---TAALSANATHSYPSRRPPDGRENDELLRLKAAGAA--GE-----------MQRATSAA 519
            :|.|   ...:..............|..|.:|.....:|.|:  ||           .|:...:.
Mosquito   392 VDEALEEEEEVEEEEVEEEEEEEEEDAEEEEEQQEHVSAQASRPGEDVTDSSIGSVPYQQVLPSP 456

  Fly   520 AVILTEKGTAASAEAVQIQSSKEAANGKINVQ-------------------------VTVL---- 555
            |.|...||    ||:.:.:..:|..||.::.:                         |.::
Mosquito   457 AQINQTKG----AESEEEEEEEEEENGSVSSEPYSSSNPSADSSMTESETDELLPRPVPIISRPT 517

  Fly   556 -------------------VDTNST----------------------------HHHQQHQQQQQQ 573
                               |.:|:.                            |.:::.||....
Mosquito   518 PVPLTTQIVAPKPRVTEPPVPSNNAAPAIANNPAAPPTAPWRRARAVPTPVPRHFYEEAQQPPAD 582

  Fly   574 QQQHHHQQHVLLLQQHQQLQQHQQQQQQQQQQQHVALDGYSATLANLKKQRSLSRTANVLNTF-E 637
            ....:..   |:....:.|...::.:..:..             ..|::.:|..........: |
Mosquito   583 DVVDYAN---LVFTSKRNLVSEKENKPTEPD-------------VILRRTQSFESDEKFYQRYAE 631

  Fly   638 LSSQTASNAHPIAAANATTTNGSVLGAGGSSSNNNNNLSTSNNNNNGSAPISTQPTLGHMGAGSV 702
            |.::..:|:.|.....:|..|...     |:::||||.|::|||||.|...:|..|.......|.
Mosquito   632 LRARIQANSCPHTILPSTPINTKT-----STASNNNNNSSNNNNNNNSTTTTTTATTPASNISSY 691

  Fly   703 LSDFEGSSPAGSSLNKFSGITGDVVTDSTSSS 734
            |.....|.....:|.|   .|.::|..||::|
Mosquito   692 LVQRSASLKDHRTLRK---TTSNLVLGSTTTS 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYPT-75D	NP_649049.1	ANKYR	123..366	CDD:440430	101/250 (40%)
		ANK repeat	123..149	CDD:293786	9/25 (36%)
		ANK repeat	151..182	CDD:293786	17/30 (57%)
		ANK repeat	184..215	CDD:293786	16/30 (53%)
		ANK repeat	217..310	CDD:293786	34/100 (34%)
		Ank_4	<259..300	CDD:372654	17/48 (35%)
		ANK repeat	312..343	CDD:293786	16/30 (53%)
Mbs	XP_061505057.1	None