Protein Alignment MYPT-75D and LOC100487727

DIOPT Version :10

• Sequence 1: NP_649049.1
• Gene: MYPT-75D / 40032
• FlyBaseID: FBgn0036801
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_031756415.1
• Gene: LOC100487727 / 100487727
• XenbaseID: XB-GENE-29078875
• Length: 908
• Species: Xenopus tropicalis
• Alignment Length: 762
• Identity: 190/762 - (24%)
• Similarity: 300/762 - (39%)
• Gaps: 202/762 - (26%)

  Fly    43 RLQLARLRRAQQLKLSRQKDKEWAKLQRAKGNTASGGSGTGSLGNGLMNGNGDTTHHFRHANGSG 107
            |...|:::|.:||       ..|.            ||.|...|                  |.|
 Frog     8 RSDAAKVKRKEQL-------NRWM------------GSETERCG------------------GPG 35

  Fly   108 TLSGRRHISFENSVVLLEAASRNDMPEVAALLQHGITPDAANEDGLTAMHQACIDNNVEMLQLLL 172
            .......:.|....|.:.|.|..|..||..||..|...:..|.|||||:||||||.|:||:|.|:
 Frog    36 VSRRAARVRFAQGAVFMAACSAGDRDEVRELLAAGAPINGTNVDGLTALHQACIDENIEMVQFLV 100

  Fly   173 EYGANVDAQDSDKWTPLHAAATCGHLELVRILIRHGANLLAVNTDGNMPYDLCDDEKTLDFIEGE 237
            |.|:||:..|::.||||||||:||.:.:.:.||.:||::.|||::|.:|.|:..:......::.|
 Frog   101 ENGSNVNQPDNEGWTPLHAAASCGFVSIAQFLITNGASVAAVNSEGELPLDVSHESAMEKLLKSE 165

  Fly   238 MAQRGVTQELIDETRSSTERIMLRDLMELARTG--GDLEEPDYQCATPLHIAAANGYVRVVEFLL 300
            :.::||.   .|..|...|.:||||:......|  .|:..|. ..||.||:|:|.||..|:..||
 Frog   166 VKKQGVD---ADVARREEEEVMLRDVRHWLNCGKAEDVRHPT-TGATTLHVASAKGYNEVIRLLL 226

  Fly   301 EQHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADLNVRNKDDETPSDICEDPEIRERIEQL 365
            :...:|||.|.|.|||:||||.||..|...:|.:...|:.:.||..:|..|:.:| .:...:|:|
 Frog   227 QLGFDVDARDFDGWTPLHAAAHWGQEEACRLLVEALCDMEIINKVGQTAMDVADD-SLESVLEKL 290

  Fly   366 KTEQ-----ESKRLAE--AQRRRVRRSQSNNTRAQSVRRTSLRDKTLTTKKDAVEE--------- 414
            |.:|     |.|::|.  ..:..:.::.:|.:|..|:.|.|.::|.....:|....
 Frog   291 KDKQSVLRLEKKKMAPQIMNQTSLNQNAANKSRRSSISRMSSQEKVALRVQDKERRAQPPPPVGL 355

  Fly   415 ----TRLRLQAQEATDSEAPSSAGDPLTNGYGYGNNNGEKR--------------------PSTG 455
                |.:...|:..:|:|:.........|     |.|.:.|                    |::|
 Frog   356 PSIPTAVGSDAESGSDTESQKVKAQERIN-----NLNNQLRNLPEPAAKKTSSLQDQEKSEPASG 415

  Fly   456 SSNGQPLPHSKSADALDNAT-------AALSANATHSYPSRR------------PP--------- 492
            |.... |..:.|..||...|       |||..:|:.|..|.|            ||
 Frog   416 SWRAS-LRKTGSTGALSTGTAPEEGRRAALPKSASSSQLSEREKAGSELRLARVPPNQKLFSNQE 479

  Fly   493 -----------------DG--------RENDELLRLKAAGAAGEMQRATSAAAVILTEKGTAASA 532
                             ||        |:..|.|..|...:....:..|......:..|...|:.
 Frog   480 NARDTVLGQRSYLRQRTDGEDSISSLRRQRGETLANKTENSIPRRELLTPKPEAPVPNKTPIAAK 544

  Fly   533 EAVQIQS-----SKEAANGKINVQVTVLVDTNSTHHHQQH---------QQQQQQQQQHHHQ--- 580
            |..||.:     .:......|......:|:|.:....:.:         :.|::.:.:|..|
 Frog   545 EENQISTPDALGRRTGTTNAITTNTVPVVNTETKERRRSYLTPVRDEEAEAQRKARSRHARQSRR 609

  Fly   581 --QHVLL--LQQHQQLQQHQ---------------QQQQQQQQQQHVALDG-----------YSA 615
              |.|.|  |::.:::.:.|               |:::..::.|..|..|           :.|
 Frog   610 STQGVTLTDLKEAEKVMKGQQDNKEAEATPEPVKAQEEETNRESQVKARTGRGASEEGTEVSWRA 674

  Fly   616 TLANLKKQRSLSRTANVLNTFELSSQTASNAHPIAAANATTTNGSVL 662
            .:|:|:|...|..|.      ..|:.|:|.:|      ..||.|..|
 Frog   675 RIASLQKSDLLGLTT------PDSAPTSSGSH------RRTTGGQSL 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYPT-75D	NP_649049.1	ANKYR	123..366	CDD:440430	97/244 (40%)
		ANK repeat	123..149	CDD:293786	8/25 (32%)
		ANK repeat	151..182	CDD:293786	20/30 (67%)
		ANK repeat	184..215	CDD:293786	15/30 (50%)
		ANK repeat	217..310	CDD:293786	30/94 (32%)
		Ank_4	<259..300	CDD:372654	16/42 (38%)
		ANK repeat	312..343	CDD:293786	13/30 (43%)
LOC100487727	XP_031756415.1	ANKYR	51..303	CDD:440430	101/256 (39%)
		ANK repeat	51..77	CDD:293786	8/25 (32%)
		ANK repeat	79..110	CDD:293786	20/30 (67%)
		ANK repeat	112..143	CDD:293786	15/30 (50%)
		ANK repeat	145..236	CDD:293786	30/94 (32%)
		ANK repeat	238..269	CDD:293786	13/30 (43%)
		IPD_PPP1R12	575..624	CDD:424067	8/48 (17%)
		PRKG1_interact	808..908	CDD:464927