Protein Alignment MYPT-75D and ppp1r16b

DIOPT Version :10

• Sequence 1: NP_649049.1
• Gene: MYPT-75D / 40032
• FlyBaseID: FBgn0036801
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001123752.1
• Gene: ppp1r16b / 100170500
• XenbaseID: XB-GENE-982398
• Length: 542
• Species: Xenopus tropicalis
• Alignment Length: 553
• Identity: 210/553 - (37%)
• Similarity: 281/553 - (50%)
• Gaps: 127/553 - (22%)

  Fly    27 DLVAEMQTVESLPTHERLQLARLRRAQQLK--LSRQKDKEWAKLQRAKGNTASGGSGTGSLGNGL 89
            ||..|:|.:|...|.|||:.|:.||.||||  ..|:|::|..:.::.|.|
 Frog     2 DLFTELQLLEKASTLERLRAAKKRREQQLKRWTQREKEEENRRRRQQKVN--------------- 51

  Fly    90 MNGNGDTTHHFRHANGSGTLSGRRHISFENSVVLLEAASRNDMPEVAALLQHGITPDAANEDGLT 154
                          ..:.|:..:| :||...|.|.||..|||..||.:||::.:.||.:||||||
 Frog    52 --------------RKTPTIRSKR-VSFPPRVTLHEACLRNDPEEVLSLLKNNVDPDLSNEDGLT 101

  Fly   155 AMHQACIDNNVEMLQLLLEYGANVDAQDSDKWTPLHAAATCGHLELVRILIRHGANLLAVNTDGN 219
            |:||.||||..::|:|||.:.|||:..|::.||||||||||||..||||||:|||:|||||.|||
 Frog   102 ALHQCCIDNYEDLLKLLLSHCANVNVTDNELWTPLHAAATCGHTNLVRILIQHGADLLAVNADGN 166

  Fly   220 MPYDLCDDEKTLDFIEGEMAQRGVTQELIDETRSSTERIMLRDLMELARTGGDLEEPDYQCATPL 284
            |.||||:||.|||.||..:..||:|||:|:|.|.:.||.||.|:..|...|.||...|.|.||.|
 Frog   167 MAYDLCEDEATLDVIESCLTYRGITQEMINEARQAPERHMLNDIRALVAIGHDLNRTDNQGATLL 231

  Fly   285 HIAAANGYVRVVEFLLEQHVNVDAMDKDLWTPVHAAACWGHLEVLEMLAQCGADLNVRNKDDETP 349
            ||||:.|:..|.|.|||...:|:..|.|:|.|:||||.||.:.|.|:|...||.|:.:...||||
 Frog   232 HIAASRGFAEVAEMLLENGAHVEVKDPDVWEPLHAAAFWGQIYVAEVLVSHGASLSAKTALDETP 296

  Fly   350 SDICEDPEIRERIEQLKTEQESKRLAEAQRRR----VRRSQSNNTRAQSVRRTSLRDKT----LT 406
            .|:|||.|:|..:.:||.:.:.  :.::|::.    .|||.|..:..:.|||.||.::|    ..
 Frog   297 LDLCEDEELRSLLLELKHKHDI--IMKSQQKNKSSLSRRSSSTGSHGKVVRRASLSERTNLYRRE 359

  Fly   407 TKKDAV-----------------EETRLRLQAQEATDSE----------------------APSS 432
            .:|:||                 ||:...:|.:.:.|||                      .||.
 Frog   360 YEKEAVVWQCLVSSGNTEGTQDEEESSPEVQQRASLDSEQTLGPSESQFRNGFCPPLPSCYCPSP 424

  Fly   433 AGD-----PLTNGYGYGNNNGEKRPS-TGSSNGQPLPHSKSADALDNATAALSANATHSYPSRRP 491
            ..|     |||||     |.....|. |||    ||..|    .||.|...||
 Frog   425 LPDIPVPTPLTNG-----NISHSLPCYTGS----PLWSS----ILDQAPLTLS------------ 464

  Fly   492 PDGRENDELLRLKAAGAAG--------EMQRAT 516
                   ||.|.::|...|        ::||.|
 Frog   465 -------ELKRQRSAAKQGRLMLKNNSDLQRLT 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYPT-75D	NP_649049.1	ANKYR	123..366	CDD:440430	133/242 (55%)
		ANK repeat	123..149	CDD:293786	12/25 (48%)
		ANK repeat	151..182	CDD:293786	18/30 (60%)
		ANK repeat	184..215	CDD:293786	24/30 (80%)
		ANK repeat	217..310	CDD:293786	48/92 (52%)
		Ank_4	<259..300	CDD:372654	19/40 (48%)
		ANK repeat	312..343	CDD:293786	15/30 (50%)
ppp1r16b	NP_001123752.1	ANK repeat	259..289	CDD:293786	15/29 (52%)
		ANKYR	70..299	CDD:440430	127/228 (56%)
		ANK repeat	70..96	CDD:293786	12/25 (48%)
		ANK repeat	98..129	CDD:293786	18/30 (60%)
		ANK repeat	131..162	CDD:293786	24/30 (80%)
		ANK repeat	226..257	CDD:293786	15/30 (50%)