Protein Alignment bora and BORA

DIOPT Version :9

• Sequence 1: NP_649048.1
• Gene: bora / 40031
• FlyBaseID: FBgn0259791
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001273675.2
• Gene: BORA / 79866
• HGNCID: 24724
• Length: 559
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 154/606 - (25%)
• Similarity: 228/606 - (37%)
• Gaps: 193/606 - (31%)

  Fly    65 TP-PPKRLHKVRNPFEG-AMADRLHLPLIASPSLFRSRTPQLSSTQFEWNIDEVSQLKPADVEPH 127
            || .|.|: .|.||||. :....||...:||||:|:| |...:..:|.|:||:::.:.|.:::|.
Human    12 TPETPGRI-PVLNPFESPSDYSNLHEQTLASPSVFKS-TKLPTPGKFRWSIDQLAVINPVEIDPE 74

  Fly   128 ETQ------FHDSPDPEQESKAQLAISAFFKESLIVPSP---------VDCPLRKQRIILNCSED 177
            :..      .|...|.:.|.|.|.||..||.:.:|||||         ..|...|      |:..
Human    75 DIHRQALYLSHSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSQCHSSK------CTNI 133

  Fly   178 N--TPISNK---SRRMRDCEVQTELTLPPILPKALEDALRPYFQPHLAGRLSGRSKSSGGPDIFN 237
            |  :|:..|   .....|...||.|:||  :...||:.|..||:   |...:.:|..    ::.:
Human   134 NSDSPVGKKLTIHSEKSDAACQTLLSLP--VDFNLENILGDYFR---ADEFADQSPG----NLSS 189

  Fly   238 SSMRRKLFDLHNVIVLGEQDTAEPSRSMVGSSPQGKQTMFAGRLSDSASGESSFGC-LSPIRNLC 301
            ||:|||||...|..:.....:|.|     ||...|.||          |.|..:.. |||::  |
Human   190 SSLRRKLFLDGNGSISDSLPSASP-----GSPHSGVQT----------SLEMFYSIDLSPVK--C 237

  Fly   302 GLPPGTPDNGTCSGK------RKLLMHELELPSPIAPSEHLSRRLVHSKVEISVTEQHDTLSERT 360
            ..|..||.:|..|..      :|..:..:..||||:..       ..|.:|..:.|  ..|||:.
Human   238 RSPLQTPSSGQFSSSPIQASAKKYSLGSITSPSPISSP-------TFSPIEFQIGE--TPLSEQR 293

  Fly   361 ALKFT---PDRSSSPMGGGLEH--------SDCS--INQRVRRLRVNS----TRQVVIETGDQPL 408
              |||   ||.||.....|:.:        ..||  .|....||::.|    .|..||:.   |.
Human   294 --KFTVHSPDASSGTNSNGITNPCIRSPYIDGCSPIKNWSPMRLQMYSGGTQYRTSVIQI---PF 353

  Fly   409 FEETEGEEEEAES---EDDEEADAMQLSTVSFNCSSSNSDTPRGHKRHRSAQRKNLSQSFSANLE 470
            ..||:||:||.:.   ..|..:.||..:.:.....|:.:.|   |..|......:::|:.|:..|
Human   354 TLETQGEDEEDKENIPSTDVSSPAMDAAGIHLRQFSNEAST---HGTHLVVTAMSVTQNQSSASE 415

  Fly   471 EE------------------------ADQT------------------QGGAGSIQ-------PA 486
            :|                        ||:|                  .|.|.||:       |.
Human   416 KELALLQDVEREKDNNTVDMVDPIEIADETTWIKEPVDNGSLPMTDFVSGIAFSIENSHMCMSPL 480

  Fly   487 EPPSVAMPQQGARIPLYRADSGFN----------------------------ETSSTTFAFSQDL 523
            ...|| :|.:.:.|.:   |||:|                            |:.|..|...||
Human   481 AESSV-IPCESSNIQM---DSGYNTQNCGSNIMDTVGAESYCKESDAQTCEVESKSQAFNMKQD- 540

  Fly   524 PLDVSMAC---------CSTP 535
              ..:..|         ||:|
Human   541 --HTTQRCWMKTASPFQCSSP 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bora	NP_649048.1	BORA_N	60..258	CDD:317655	65/214 (30%)
BORA	NP_001273675.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		8/15 (53%)
		BORA_N	7..213	CDD:317655	66/217 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160341
Domainoid	1	1.000	68	1.000	Domainoid score	I9765
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I5164
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto88931
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14728
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4486
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.980