Protein Alignment not and UBP8

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_013950.1
• Gene: UBP8 / 855263
• SGDID: S000004836
• Length: 471
• Species: Saccharomyces cerevisiae
• Alignment Length: 518
• Identity: 162/518 - (31%)
• Similarity: 246/518 - (47%)
• Gaps: 91/518 - (17%)

  Fly   213 CRHYQS-YVKEHSYDTFRVIDAYFAA--CVNRDARERKAIHCNCFECGS-YGIQ---LYACLHCI 270
            |.|.|. :..|.|.|  .|:....||  .:|....:.|.:  |..:||: :.|.   .:.||.|.
Yeast     4 CPHIQQVFQNEKSKD--GVLKTCNAARYILNHSVPKEKFL--NTMKCGTCHEINSGATFMCLQCG 64

  Fly   271 YFGC-RGAHITSHLRSKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKLEAKDLQKSIGW 334
            :.|| ..:|..||.:...|...:..::|.|:|:.|.|:|     ....|||..:.||
Yeast    65 FCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYI-----GNIDLINDAILAK-------- 116

  Fly   335 VPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRH- 398
             .|.....:|  ::.:..||       .||.||:|:|:||||:.|:|.|:|.|....:.||..|
Yeast   117 -YWDDVCTKT--MVPSMERR-------DGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHS 171

  Fly   399 -DCGSKSSHKCLVCEVSRLFQEFY------SGSRSPLSLHR------LLHLIWNHAKHLAGYEQQ 450
             :|..:|..||..|.:.::..|.|      ..|.|..|.:|      ||...|...::||||.||
Yeast   172 NNCKVRSPDKCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQ 236

  Fly   451 DAHEFFIATLDVLHRHCV--KAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGML 513
            |||||:...::.:|:..|  ...|:..|::|:.                  ||.||:..:|.|.|
Yeast   237 DAHEFWQFIINQIHQSYVLDLPNAKEVSRANNK------------------QCECIVHTVFEGSL 283

  Fly   514 QSDVVCQAC-NGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTC 577
            :|.:||..| |...||.|||.|:|||:.:        .|.|.:||:.:.:.|.| ......|..|
Yeast   284 ESSIVCPGCQNNSKTTIDPFLDLSLDIKD--------KKKLYECLDSFHKKEQL-KDFNYHCGEC 339

  Fly   578 KSYQESTKQFSLRTLPSVVSFHLKRFEHSALI---DRKISSFIQFPVEFDMTPFMSEK-KNAYG- 637
            .|.|::.||..:..||||:...||||||  |:   :||:..||:||...:|..:.|.| |:.:.
Yeast   340 NSTQDAIKQLGIHKLPSVLVLQLKRFEH--LLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSE 402

  Fly   638 -----DFRFSLYAVVNHVGTIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFY 695
                 |..:.|..:|:|.||::.|||.|:.:.....|.|.:|.:::..|.::||..:.|||||
Yeast   403 NGKVPDIIYELIGIVSHKGTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFY 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464	18/61 (30%)
		Peptidase_C19D	365..696	CDD:239125	121/358 (34%)
UBP8	NP_013950.1	zf-UBP	46..108	CDD:460464	18/66 (27%)
		Peptidase_C19D	138..466	CDD:239125	121/357 (34%)