Protein Alignment not and UBP12

DIOPT Version :9

• Sequence 1: NP_001287106.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_012338.1
• Gene: UBP12 / 853242
• SGDID: S000003733
• Length: 1254
• Species: Saccharomyces cerevisiae
• Alignment Length: 756
• Identity: 120/756 - (15%)
• Similarity: 181/756 - (23%)
• Gaps: 424/756 - (56%)

  Fly   156 GLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSS-----HKCLVCEVSRLFQEFYS 215
            |..||:|||.||:||..:|.|||.|.|.|||:.|.::......     |..:....|.|.|:.:.
Yeast   362 GTTGLVNLGNTCYMNSALQCLVHIPQLRDYFLYDGYEDEINEENPLGYHGYVARAFSDLVQKLFQ 426

  Fly   216 GSRS--------PLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSN 272
            ...|        |.|:.:  ..|.:.....:||.|||:.||....||.||....:...:..::..
Yeast   427 NRMSIMQRNAAFPPSMFK--STIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLNRIIKKEYTEKP 489

  Fly   273 SSGSGSGTNSSN--------SSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPF---- 325
            |...|...|..|        :...|....|:.|.| :|.||.:|.:.|..|..||.|:||:
Yeast   490 SLSPGDDVNDWNVVKKLADDTWEMHLKRNCSVITD-LFVGMYKSTLYCPECQNVSITFDPYNDVT 553

  Fly   326 --------WD--------------ISLDLGETTTH----------GGVTPKTLI----------- 347
                    ||              :.::|.:::|:          .|:.|.||.
Yeast   554 LPLPVDTVWDKTIKIFPMNSPPLLLEVELSKSSTYMDLKNYVGKMSGLDPNTLFGCEIFSNQIYV 618

  Fly   348 ----------------------------------------------------------------- 347
                                                                             
Yeast   619 NYESTESNAQFLTLQELIKPADDVIFYELPVTNDNEVIVPVLNTRIEKGYKNAMLFGVPFFITLK 683

  Fly   348 ----------------------------------------------------------------- 347
                                                                             
Yeast   684 EDELNNPGAIRMKLQNRFVHLSGGYIPFPEPVGNRTDFADAFPLLVEKYPDVEFEQYKDILQYTS 748

  Fly   348 ----------------------------------------------------------------- 347
                                                                             
Yeast   749 IKVTDKDKSFFSIKILSVEKEQQFASNNRTGPNFWTPISQLNLDKATDIDDKLEDVVKDIYNYSS 813

  Fly   348 ----------------------------------------------------------------- 347
                                                                             
Yeast   814 LVDCAEGVLMQVDDEGDTEGSEAKNFSKPFQSGDDEENKETVTNNENVNNTNDRDEDMELTDDVE 878

  Fly   348 ----------------------------------------------------------------- 347
                                                                             
Yeast   879 EDASTEPELTDKPEALDKIKDSLTSTPFAILSMNDIIVCEWSELGSNEAFSDDKIYNWENPATLP 943

  Fly   348 ----------------------DCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVS 390
                                  |||:.:::.|.||......|.|||.::::|||..|...|.::.
Yeast   944 NKELENAKLERSNAKERTITLDDCLQLFSKPEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILL 1008

  Fly   391 FHLKRFEHSALIDRKISSFIQFPV-EFDMTPFMSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAY 454
            .||||||.......||.:.:.||: :.|::.::..|.:..| ..:.||||.||.|.:..||||||
Yeast  1009 IHLKRFESQRSFSDKIDATVNFPITDLDLSRYVVYKDDPRG-LIYDLYAVDNHYGGLGGGHYTAY 1072

  Fly   455 VRHQKDT-WVKCDDHVITMASLKQVLDSEGYLLFY---HKN 491
            |::..|. |...||..:|..:.:..:....|||||   ||:
Yeast  1073 VKNFADNKWYYFDDSRVTETAPENSIAGSAYLLFYIRRHKD 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
		Peptidase_C19D	158..489	CDD:239125	117/750 (16%)
UBP12	NP_012338.1	UBP12	99..1111	CDD:227847	118/752 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940