DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and UBP13

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_009486.3	Gene:	UBP13 / 852212	SGDID:	S000000163	Length:	747	Species:	Saccharomyces cerevisiae

Alignment Length:	344	Identity:	85/344 - (24%)
Similarity:	153/344 - (44%)	Gaps:	61/344 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 ALVHTPLLS-DYFMSDRHDCGSKSSHKCLVCEVSRLFQ-----EFYSGSRSPLSLHRLL---HLI 230
            ||:..|:|: |:.::.       |....|...:..:|:     .:.:|..||.|...:|   :::
Yeast   368 ALIRGPVLNIDHSLNG-------SDKATLYSSLRDIFECITENTYLTGVVSPSSFVDVLKRENVL 425

  Fly   231 WNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCN 295
            :|...|      |||||||...|:.|        :|:..:.|...:.|..||.:..|     :..
Yeast   426 FNTTMH------QDAHEFFNFLLNEL--------SEYIERENKKIAASDINSDSEPS-----KSK 471

  Fly   296 CIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDL-GETTTHGGVTPKTLIDCLERYTRAEHL 359
            ..|..:|.|.|.:.:.|..|:.:::..:||.|..::: |:..|       .:.:.|:.|.:.|.|
Yeast   472 NFISDLFQGTLTNQIKCLTCDNITSRDEPFLDFPIEVQGDEET-------DIQEILKSYHQREML 529

  Fly   360 GSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSF--IQFPVEFDMTPFM 422
            ..:.|..|..|...||:.:...|:.||..::.|||||::|...:..|..|  |.:|:..::...:
Yeast   530 NGSNKFYCDECCGLQEAERLVGLKQLPDTLTLHLKRFKYSEKQNCNIKLFNNIHYPLTLNVCSSI 594

  Fly   423 SEKKNAYGDFRFSLYAVVNHV-GTIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEG--- 483
            :.|...    ::.|..:|.|: |....|||.:..:|:|..|:..||..:.....:.||:..|
Yeast   595 NSKVCQ----KYELAGIVVHMGGGPQHGHYVSLCKHEKFGWLLFDDETVEAVKEETVLEFTGESP 655

  Fly   484 -----YLLFY---HKNVLE 494
                 |:|||   :.|.:|
Yeast   656 NMATAYVLFYKAMYSNAVE 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	83/337 (25%)
UBP13	NP_009486.3	Peptidase_C19	141..>165	CDD:351799
UBP13	NP_009486.3	Peptidase_C19G	388..666	CDD:239128	76/307 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910