DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and DOA4

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_010354.3	Gene:	DOA4 / 851641	SGDID:	S000002476	Length:	926	Species:	Saccharomyces cerevisiae

Alignment Length:	389	Identity:	108/389 - (27%)
Similarity:	168/389 - (43%)	Gaps:	86/389 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 GLLNLGATCFMNCIVQALVHTPLLSDYFMSDRH----DCGSKSSHKCLVCE-----VSRLFQEFY 214
            ||.|||.:|:||||:|.::.|..|:..|:.|.:    :..||...|.::.:     |..:::|..
Yeast   563 GLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYKEQV 627

  Fly   215 SGSR----SPL-------SLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLH---RHC----- 260
            .||:    ||:       |::.|....          .|||..||....||.||   ..|
Yeast   628 DGSKKISISPIKFKLACGSVNSLFKTA----------SQQDCQEFCQFLLDGLHEDLNQCGSNPP 682

  Fly   261 -----VKAKAEHESKSNSSGSG------SGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQA 314
                 .:|:|..|..|....|.      ..|:.|             :|..:|.|...|.:.|:.
Yeast   683 LKELSQEAEARREKLSLRIASSIEWERFLTTDFS-------------VIVDLFQGQYASRLKCKV 734

  Fly   315 CNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQ 379
            |:..||||.||..:|:.:.:..:...:   |:.||...:|:.|:|....:..|..|:..|.||||
Yeast   735 CSHTSTTYQPFTVLSIPIPKKNSRNNI---TIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQ 796

  Fly   380 FSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEK----------------KNA 428
            .::..||..:..|||||::   :..|.:.|:.:|...|:|||.:..                :..
Yeast   797 LTITRLPRNLIVHLKRFDN---LLNKNNDFVIYPFLLDLTPFWANDFDGVFPPGVNDDELPIRGQ 858

  Fly   429 YGDFRFSLYAVVNHVGTIDTGHYTAYVRH-QKDTWVKCDDHVITMASLK-QVLDSEGYLLFYHK 490
            ...|::.||.|..|.||:..|||||||:. .|..|:..||........| ..::|..|:||||:
Yeast   859 IPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYKPVKNKADAINSNAYVLFYHR 922

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	106/386 (27%)
DOA4	NP_010354.3	RHOD	208..324	CDD:197731
DOA4	NP_010354.3	COG5533	495..924	CDD:227820	108/389 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910