DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and UBP6

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_116665.1	Gene:	UBP6 / 850562	SGDID:	S000001906	Length:	499	Species:	Saccharomyces cerevisiae

Alignment Length:	440	Identity:	87/440 - (19%)
Similarity:	159/440 - (36%)	Gaps:	103/440 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 TKETNLLLANARRRL----VRPNQTIGL-----RGLLNLGATCFMNCIVQALVHTPLLSDYFMSD 189
            |.:.||:...|::..    :.|.|.:..     .|..|:|.||::|..:|||.....|.|..::.
Yeast    76 TPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRDMILNY 140

  Fly   190 RHDCGSKSS-------HKCLVCEVSRLFQEFYSGSRS---PLSLHRLLHLIWNH--AKHLAG--Y 240
            ....|..:|       ||.:|.|:.|.|:...:.|..   |:.|...|...:..  .:...|  |
Yeast   141 NPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERDSQGGFY 205

  Fly   241 EQQDAHEFFIATLDVLHRHC------------VKAKAEHESKSNSSGSGSGTNSSNSS-SSHCYG 292
            :||||.|.|   ..:.|...            ::.|...:..:|.:......|.|:|. ..|..|
Yeast   206 KQQDAEELF---TQLFHSMSIVFGDKFSEDFRIQFKTTIKDTANDNDITVKENESDSKLQCHISG 267

  Fly   293 QCNCIIDQIFTGMLQSDVVCQACNGVSTTYDP------------------FWDISLDLGETTTHG 339
            ..|.:.:.:..|:.:.........|.::.|..                  ||..|.:........
Yeast   268 TTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPKFLTVQYVRFFWKRSTNKKSKILRK 332

  Fly   340 GVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQE-STKQFSLRTLPSVVSFHLKRFEHSALID 403
            .|.|..| |..:..| .|:.....|::....|..:| :.|:..::.         ::|:.|:
Yeast   333 VVFPFQL-DVADMLT-PEYAAEKVKVRDELRKVEKEKNEKEREIKR---------RKFDPSS--- 383

  Fly   404 RKISSFIQFPVEFDMTPFM---SEKKNAYGDFR----------------FSLYAVVNHVG-TIDT 448
               |..:..|.|...|...   |||.....:::                ::|..|:.|.| ..::
Yeast   384 ---SENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYNLIGVITHQGANSES 445

  Fly   449 GHYTAYVRHQKD--TWVKCDDHVITMASLKQVL------DSEGYLLFYHK 490
            |||.|::|.:.|  .|.|.:|..:::...:::.      :|:..|:..:|
Yeast   446 GHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALILMYK 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	80/404 (20%)
UBP6	NP_116665.1	Ubiquitin_like_fold	5..78	CDD:421700	1/1 (100%)
UBP6	NP_116665.1	Peptidase_C19A	110..495	CDD:239122	80/404 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910