Protein Alignment not and USP42

DIOPT Version :9

• Sequence 1: NP_001287106.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001376579.1
• Gene: USP42 / 84132
• HGNCID: 20068
• Length: 1327
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 112/415 - (26%)
• Similarity: 192/415 - (46%)
• Gaps: 66/415 - (15%)

  Fly   103 DARSREYALINRKLEAKDLQKSIGWVPWV-------------PTTKETNLL---LANARRRLVRP 151
            ||.|..:..::...:..:...|:|.||..             |:.::...|   :|..::.|. |
Human    32 DAGSASWGAVSSLNDVSNHTLSLGPVPGAVVYSSSSVPDKSKPSPQKDQALGDGIAPPQKVLF-P 95

  Fly   152 NQTIGLR---------GLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHK---CLVC 204
            ::.|.|:         ||.|||.|||.|..:|.|.:||.|::|.:|..|   ||:.|.   |::|
Human    96 SEKICLKWQQTHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEH---SKTCHAEGFCMMC 157

  Fly   205 EVSRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHES 269
            .:.....:..|.....:....:::.:...|:|.....|:|||||...|:|.:.:.|:
Human   158 TMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACL-------- 214

  Fly   270 KSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGE 334
                       |.||....|.  |...::.|||.|.|:|.|.|..|.|||.|:||:.||:|::
Human   215 -----------NGSNKLDRHT--QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEI-- 264

  Fly   335 TTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHS 399
                  ...:::...||::.:.|.|......|||.||....::|:|::....:|::..||||.:
Human   265 ------KAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFAN- 322

  Fly   400 ALIDRKISSFIQFPVEFDMTPFMSEKKNAYGDFRFSLYAVVNHVG-TIDTGHYTAYVRHQKDTWV 463
             ....||:..:::|...|:.|:||:....  ...:.||||:.|.| ....|||..|::.....|.
Human   323 -FTGGKIAKDVKYPEYLDIRPYMSQPNGE--PIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWY 384

  Fly   464 KCDDHVITMASLKQVLDSEGYLLFY 488
            :.:|.:::.:.::.||..:.|:|||
Human   385 QMNDSIVSTSDIRSVLSQQAYVLFY 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	112/415 (27%)
		Peptidase_C19D	158..489	CDD:239125	98/344 (28%)
USP42	NP_001376579.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		3/5 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..87		2/23 (9%)
		Peptidase_C19E	110..410	CDD:239126	98/336 (29%)
		PHA03247	<422..938	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	452..494
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	536..707
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	722..1026
		PRK07764	<735..940	CDD:236090
		PRK12678	846..>1113	CDD:237171
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1085..1131
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1149..1254
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1275..1294

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D929408at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920