DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and UBP11

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_174562.2	Gene:	UBP11 / 840179	AraportID:	AT1G32850	Length:	892	Species:	Arabidopsis thaliana

Alignment Length:	772	Identity:	144/772 - (18%)
Similarity:	223/772 - (28%)	Gaps:	322/772 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 YVKEHSYDTFRVIDAYFAACVNRDARERKAIHCNCFECGSYGIQLYACLHCIYFGCRG------- 69
            |.|..|      ::.|.......|:|:.........:..|.| |||..:      |.|
plant   137 YTKSFS------VEVYLLCLTLTDSRDESTTIIRLSKQASIG-QLYEMV------CAGKGVAKEK 188

  Fly    70 AHITSHLRSKK--------------------HNVALELSHGTLYCYACRDFIYDARSREYALI-- 112
            |.|..:...||                    .::.||:...     |...|:......|.|::
plant   189 ARIWDYFEKKKSVLLDPSSEQSVEEAGLQFNQDILLEVDGS-----ASSQFVMSLAENELAMVPL 248

  Fly   113 -NRKLEAKDLQKSIGWVPWVPTTKE------------TNLLLANARRRLVRPNQTIGLRGLLNLG 164
             ..:.:|.|:.:..|      |...            .|....:...|.....:..||.||.|||
plant   249 EPMRSDAMDIVRGGG------TLSNGHSNGFKFSFFGRNTFKDDVSSRTFGKGEKRGLGGLQNLG 307

  Fly   165 ATCFMNCIVQALVHTPLLSDYFMSD-RHDCGSKS---SHKCLVCEVSRLFQEFYSGSRSPLSLHR 225
            .|||||..:|.|.|||.:.:||:.| |.|..:|:   ....|......|.::.:|..::.::...
plant   308 NTCFMNSTLQCLAHTPPIVEYFLQDYRSDINAKNPLGMRGELAIAFGELLRKLWSSGQNTVAPRA 372

  Fly   226 LLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHR--HCVKAKAEHESKSNSSGSGSGTNSSNSSSS 288
            ....:...|...:||.|.|:.|.....||.||.  :.||.|...|:| :|.|......:......
plant   373 FKTKLARFAPQFSGYNQHDSQEMLAFLLDGLHEDLNKVKRKPYIEAK-DSDGRPDDEVAEEKWKY 436

  Fly   289 HCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTH--------------- 338
            |.....:.|:| :|.|..:|.:||..|..:|.|:|||..:||.|..:.|.
plant   437 HKARNDSVIVD-VFQGQYKSTLVCPDCGKISITFDPFMYLSLPLPSSRTRSMTVTVFYGDGSHLP 500

  Fly   339 ----------------------------------------------------------------- 338

plant   501 MPYTVTVPKDGSCRDLSNALGTACCLDNDESLLLAEVYDHKVFKYYENPRELLNGIKDNEHIVAY 565

  Fly   339 ----------------------------------------------------------------- 338

plant   566 RFKQMHKGPGKVKLEILHGEQEKSSDRGPKCFGTPLVTYINKEPLSGTDIATSISGLLSPLRRVH 630

  Fly   339 ------------------------------------------------------------GGVT- 342
                                                                        |.||
plant   631 MSCVVNSGNENGHVPDESSRSILSRDTETEDNDRELSLSLLRDYYSFNLQPLESDSVVNPGSVTK 695

  Fly   343 ---------------------PK---------------TLIDCLERYTRAEHLGSAAKIKCSTCK 371
                                 ||               :|..|||.:...|.||......|..||
plant   696 VLVKWNEKEHEKYDSSYLNDLPKVHKNVLAKKTMQEGISLFSCLEAFLAEEPLGPDDMWYCPGCK 760

  Fly   372 SYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPV-EFDMTPFMSEKKNAYG-DFRF 434
            .::::.|:..|..||.::.||||||.:|.....||.:.:.|.: :.|::.::   ||..| .:.:
plant   761 EHRQANKKLDLWKLPDILVFHLKRFTYSRYFKNKIDTLVNFHIHDLDLSKYV---KNEDGQSYLY 822

  Fly   435 SLYAVVNHVGTIDTGHYTAYVRHQKDT-WVKCDDHVITMASLKQVLDSEGYLLFYHK 490
            .|||:.||.|.:..||||||.:...:| |...||..::..:..::..|..|:|||.:
plant   823 ELYAISNHYGGLGGGHYTAYAKLMDETKWYNFDDSRVSAVNESEIKTSAAYVLFYQR 879

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	15/83 (18%)
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	112/581 (19%)
UBP11	NP_174562.2	UBP12	20..879	CDD:227847	144/770 (19%)
		DUSP	37..135	CDD:197831
		Peptidase_C19	302..>477	CDD:271592	55/176 (31%)
		Peptidase_C19R	<722..878	CDD:239139	48/158 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910