DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and UBP22

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_568239.1	Gene:	UBP22 / 830946	AraportID:	AT5G10790	Length:	557	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	188/559 - (33%)
Similarity:	281/559 - (50%)	Gaps:	96/559 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRHYQSYVKEHSYDTFRVIDAYFAACVNRDARERKAIH----CNCFECGSYGIQLYACLHCIYFG 66
            |.|...|...:..|.::..:..| .|.| |||.:..:.    ..|..|..|..:||.||.|....
plant    14 CNHLSDYKLRYGTDGYKSFNNLF-RCFN-DARIKIKLQGIDIPRCSYCSVYQKRLYICLICRSIS 76

  Fly    67 CRGAHITSHLR-SKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKLEAKDLQ-KSIGWVP 129
            | .:||..|.: :|.|::|:::....|||.||.|.:||:...| .:::::|....:. ||...|.
plant    77 C-SSHILLHTQLNKGHDIAIDVERSELYCCACIDQVYDSEFDE-VVVSKQLFGLGMSVKSGADVV 139

  Fly   130 WVPTTKETNL---------LLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDY 185
            .|.:.|:..|         .|.:.|.|..:....:|||||.|||:|||||.::|||||.|.|.::
plant   140 AVRSNKKRRLDSQLIIGSNFLVSPRDRREKWTFPLGLRGLNNLGSTCFMNAVLQALVHAPPLRNF 204

  Fly   186 FMSDRHD---CGSKS-SHKCLVCEVSRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAH 246
            ::|.:|:   |..:: ...||.|::..:|...:||.|:|.|...||:..|.|:.:||.|||||:|
plant   205 WLSGQHNRDLCPRRTMGLLCLPCDLDVIFSAMFSGDRTPYSPAHLLYSWWQHSTNLATYEQQDSH 269

  Fly   247 EFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVV 311
            ||||:.||.:|.:..|:|..::...                     :|.||..:.|:|:|:|||.
plant   270 EFFISLLDRIHENEGKSKCLYQDNE---------------------ECQCITHKAFSGLLRSDVT 313

  Fly   312 CQACNGVSTTYDPFWDISL-----------DLGETTTHGG-----VTPKTLIDCLERYTRAEHLG 360
            |..|...|||||||.||||           |..:....||     :.| ||..||:.:||:|.||
plant   314 CTTCGSTSTTYDPFIDISLTLDSMNGFSPADCRKNRYSGGPSVNAIMP-TLSGCLDFFTRSEKLG 377

  Fly   361 SAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSAL--IDRKISSFIQFPVEFDMTPFMS 423
            ...|:.|.:|...:||:||.|:|.||.::..|:||||||..  ..|||.|::|:|...:|:|::|
plant   378 PDQKLNCQSCGEKRESSKQMSIRRLPLLLCLHVKRFEHSLTRKTSRKIDSYLQYPFRLNMSPYLS 442

  Fly   424 E----KK--------NAYGDF----------RFSLYAVVNHVGTIDTGHYTAYVRHQKDTWVKCD 466
            .    |:        :..|::          .|.::|||.|.|.:::|||..|:| .|..|.:||
plant   443 SSIIGKRFGNRIFAFDGEGEYDSSSSSSPSAEFEIFAVVTHKGMLESGHYVTYLR-LKGLWYRCD 506

  Fly   467 DHVITMASLKQVLDSEGYLLFY---------HKNVLEYE 496
            |..|.....:.|...|.|:|||         ||. |.|:
plant   507 DAWINEVEEEVVRGCECYMLFYAQETVIQKAHKE-LSYQ 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	21/57 (37%)
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	138/383 (36%)
UBP22	NP_568239.1	zf-UBP	56..116	CDD:366940	23/60 (38%)
UBP22	NP_568239.1	Peptidase_C19D	177..528	CDD:239125	136/373 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	231	1.000	Domainoid score	I650
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	279	1.000	Inparanoid score	I876
OMA	1	1.010	-	-		QHG59954
OrthoDB	1	1.010	-	-		D929408at2759
OrthoFinder	1	1.000	-	-		FOG0002382
OrthoInspector	1	1.000	-	-		oto4252
orthoMCL	1	0.900	-	-		OOG6_102914
Panther	1	1.100	-	-	LDO	PTHR21646
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1575
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840