DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and UBP12

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_568171.1	Gene:	UBP12 / 830548	AraportID:	AT5G06600	Length:	1116	Species:	Arabidopsis thaliana

Alignment Length:	344	Identity:	85/344 - (24%)
Similarity:	136/344 - (39%)	Gaps:	69/344 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 GLRGLLNLGATCFMNCIVQALVHTPLL--SDYFM-SDRHDCGSKSSHKCLVCEVSRLFQEFYSGS 217
            |..||.|.||||:||.::|.|.|.|..  :.|.| :..:|..:.|
plant   197 GFVGLKNQGATCYMNSLLQTLYHIPYFRKAVYHMPTTENDAPTAS-------------------- 241

  Fly   218 RSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVK-------AKAEHESKSNSSG 275
             .||:|..|.:.:..:...:|..|.  ...|...|.|...:|.|:       .|.|.:.|
plant   242 -IPLALQSLFYKLQYNDTSVATKEL--TKSFGWDTYDSFMQHDVQELNRVLCEKLEDKMK----- 298

  Fly   276 SGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGG 340
               ||....:            |.|:|.|...:.:.|...:..||..:.|:|:.||:...
plant   299 ---GTVVEGT------------IQQLFEGHHMNYIECINVDFKSTRKESFYDLQLDVKGC----- 343

  Fly   341 VTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDR- 404
               |.:....::|...|.|....|..... ...|::.|.......|.|:...|||||:..:.|.
plant   344 ---KDVYASFDKYVEVERLEGDNKYHAEG-HGLQDAKKGVLFIDFPPVLQLQLKRFEYDFMRDTM 404

  Fly   405 -KISSFIQFPVEFDMT----PFMSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQ-KDTWV 463
             ||:...:||:|.|:.    .::|...:......::|::|:.|.|.:..|||.|::|.. .|.|.
plant   405 VKINDRYEFPLELDLDREDGKYLSPDADRSVRNLYTLHSVLVHSGGVHGGHYYAFIRPTLSDQWY 469

  Fly   464 KCDDHVITMASLKQVLDSE 482
            |.||..:|...||:.|:.:
plant   470 KFDDERVTKEDLKRALEEQ 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	84/342 (25%)
UBP12	NP_568171.1	MATH	55..179	CDD:238068
		COG5077	57..1114	CDD:227409	85/344 (25%)
		peptidase_C19C	197..526	CDD:239124	85/344 (25%)
		USP7_ICP0_bdg	625..875	CDD:289221
		USP7_C2	884..1095	CDD:291217
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910