DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and USP9Y

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_016885567.1	Gene:	USP9Y / 8287	HGNCID:	12633	Length:	2560	Species:	Homo sapiens

Alignment Length:	449	Identity:	99/449 - (22%)
Similarity:	158/449 - (35%)	Gaps:	148/449 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 VRPNQTIGLRGLLNLGATCFMNCIVQALVHTP---------------LLSDYFMSDRHDCGSKSS 198
            |.|....|..||.|.||||:||.::|.|...|               |..|.|..::.|..|...
Human  1555 VGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVD 1619

  Fly   199 HKCLVCEVSRLFQEFYSGSRSP------LSLHRLLHLIWNH--AKHLAGY--------------- 240
            .:..|......|::..:.|::.      :.:.|.|.:|:.|  |..|..|
Human  1620 PRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEP 1684

  Fly   241 ----EQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQI 301
                ||.||.|||.:.:|.|. ..:||.. |.:                           |:.::
Human  1685 VNLREQHDALEFFNSLVDSLD-EALKALG-HPA---------------------------ILSKV 1720

  Fly   302 FTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIK 366
            ..|......:||.|.......:.|..:::|:   ..|     :.|:|.||:|.:.:.|..|....
Human  1721 LGGSFADQKICQGCPHRYECEESFTTLNVDI---RNH-----QNLLDSLEQYIKGDLLEGANAYH 1777

  Fly   367 CSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHS-----ALIDRKISSFIQFPVEFDMTPF----- 421
            |..|....::.|:..::.||.|::..||||::.     |:   |.:.:.:||.|.||.|:
Human  1778 CEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECAI---KFNDYFEFPRELDMGPYTVAGV 1839

  Fly   422 -------------------MSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYV------RHQKDT 461
                               .|:.:.| |..::.|..|:.|.|....|||.:|:      ..|.|.
Human  1840 ANLERDNVNSENELIEQKEQSDNETA-GGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDH 1903

  Fly   462 WVKCDDHVITMASLK----------------QVLDS--------------EGYLLFYHK 490
            |.|.||..:|...:.                :|.|.              ..|:|||.:
Human  1904 WYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQ 1962

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	95/437 (22%)
USP9Y	XP_016885567.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910